TPMT anticorps (C-Term)
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- Antigène Voir toutes TPMT Anticorps
- TPMT (Thiopurine S-Methyltransferase (TPMT))
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Épitope
- C-Term
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Reactivité
- Humain, Chien, Porc
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp TPMT est non-conjugé
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Application
- Western Blotting (WB)
- Séquence
- RGALVAINPG DRKCYADTMF SLLGKKFQYL LCVLSYDPTK HPGPPFYVPH
- Homologie
- Dog: 79%, Human: 100%, Pig: 79%
- Attributs du produit
- This is a rabbit polyclonal antibody against TPMT. It was validated on Western Blot.
- Purification
- Affinity Purified
- Top Product
- Discover our top product TPMT Anticorps primaire
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- Indications d'application
- Optimal working dilutions should be determined experimentally by the investigator.
- Commentaires
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Antigen size: 245 AA
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- Lot specific
- Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Conseil sur la manipulation
- Avoid repeated freeze-thaw cycles.
- Stock
- -20 °C
- Stockage commentaire
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- Antigène
- TPMT (Thiopurine S-Methyltransferase (TPMT))
- Autre désignation
- TPMT (TPMT Produits)
- Synonymes
- anticorps MGC84277, anticorps AW106912, anticorps NHLRC1, anticorps thiopurine S-methyltransferase L homeolog, anticorps thiopurine S-methyltransferase, tandem duplicate 2, anticorps thiopurine S-methyltransferase TpmT, anticorps thiopurine S-methyltransferase, anticorps Thiopurine S-methyltransferase, anticorps thiopurine methyltransferase, anticorps tpmt.L, anticorps tpmt.2, anticorps tpmT, anticorps MCA0794, anticorps Pnap_4948, anticorps Hhal_1383, anticorps TK90_1044, anticorps Slit_1144, anticorps Tint_0842, anticorps Fbal_3334, anticorps Celly_3188, anticorps Weevi_1737, anticorps Psefu_2696, anticorps Metme_3860, anticorps Tpmt, anticorps TPMT
- Sujet
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This gene encodes the enzyme that metabolizes thiopurine drugs via S-adenosyl-L-methionine as the S-methyl donor and S-adenosyl-L-homocysteine as a byproduct. Thiopurine drugs such as 6-mercaptopurine are used as chemotherapeutic agents. Genetic polymorphisms that affect this enzymatic activity are correlated with variations in sensitivity and toxicity to such drugs within individuals. A pseudogene for this locus is located on chromosome 18q.
Alias Symbols: -
Protein Interaction Partner: APP, UBC,
Protein Size: 245 - Poids moléculaire
- 27 kDa
- ID gène
- 7172
- NCBI Accession
- NM_000367, NP_000358
- UniProt
- P51580
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