SNAI3 anticorps (Middle Region)

N° du produit ABIN3043345

Cet anticorps Lapin Polyclonal détecte spécifiquement SNAI3 dans WB. Il présente une réactivité avec des échantillons de Humain.

Aperçu rapide pour SNAI3 anticorps (Middle Region) (ABIN3043345)

Antigène: SNAI3 (Snail Homolog 3 (SNAI3))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp SNAI3 est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-SNAI3 anticorps

Épitope: Middle Region

Fonction: Anti-SNAI3 Antibody

Séquence: FHCHKPYHTL AGLARHRQLH CHLQ

Specificité: No cross reactivity with other proteins.

Réactivité croisée (Details): No cross-reactivity with other proteins

Homologie: different from the related mouse sequence by two amino acids.

Attributs du produit: Anti-SNAI3 Antibody. Tested in WB applications. This antibody reacts with Human.

Purification: Immunogen affinity purified.

Immunogène: A synthetic peptide corresponding to a sequence in the middle region of human SNAI3, different from the related mouse sequence by two amino acids.

Isotype: IgG

Information d'application

Indications d'application: Western blot, 0.1-0.5 μg/mL, Human

Commentaires:

Antibody can be supported by chemiluminescence kit ABIN921124 in WB.

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Concentration: 500 μg/mL

Buffer: Each vial contains antibody formulated with stabilizing components, 0.9 mg NaCl, 0.2 mg Na2HPO4, and 0.05 mg Sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C,-20 °C

Stockage commentaire: Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.

Date de péremption: 12 months

Détails sur SNAI3

Antigène: SNAI3 (Snail Homolog 3 (SNAI3))

Autre désignation: SNAI3

Sujet:

Background: SNAI3 is a member of the SNAIL gene family, named for the Drosophila snail gene, which plays roles in mesodermal formation during embryogenesis. SNAI3 gene, was located between KIAA0233 gene and CBFA2T3 gene in human chromosome 16q24.3, a region affected in breast cancer, gastric cancer, hepatocellular carcinoma, ovarian cancer, and therapy-related myeloid leukemia with t (16,21) (q24,q22) translocation. Human SNAI3 gene was found to encode 292-amino-acid polypeptide with the N-terminal SNAG domain and five zinc finger domains. And Human SNAI3 mRNA was expressed in skin melanotic melanoma, lung epidermoid carcinoma, and germ cell tumor. Because SNAG zinc-finger proteins are transcriptional repressors implicated in carcinogenesis and embryogenesis, SNAI3 gene might be a potent target of pharmacogenomics in the field of oncology and regenerative medicine.

Gene Full Name: snail family transcriptional repressor 3

Sequence Similarities: Belongs to the snail C2H2-type zinc-finger protein family.

Poids moléculaire: 32 kDa

ID gène: 333929

UniProt: Q3KNW1