Cet anticorps anti-Lysophosphatidic Acid 2 (LPA2) Receptor (EDG4) Polyclonal Lapin (ABIN306909) détecte spécifiquement Lysophosphatidic Acid 2 (LPA2) Receptor (EDG4) dans WB.
L’anticorps est réactif avec des échantillons de Humain.
Aperçu rapide pour Lysophosphatidic Acid 2 (LPA2) Receptor (EDG4) (N-Term) anticorps (ABIN306909)
Antigène
Lysophosphatidic Acid 2 (LPA2) Receptor (EDG4)
Reactivité
Humain
Hôte
Lapin
Clonalité
Polyclonal
Application
Western Blotting (WB)
Épitope
N-Term
Fonction
Rabbit anti Human Lysophosphatidic Acid 2 (LPA2) Receptor (EDG4) CT
Réactivité croisée
Humain
Attributs du produit
EDG4 belongs to a family of G-protein coupled receptors whose ligands are lysophospholipids. The ligand for EDG4 is lysophospholipid. There are 6 known members of the EDG receptor family and they are implicated in mediating growthrelated effects such as induction of cellular proliferation, alterations in differentiation and survival and suppression of apoptosis. They also evoke cellular effector functions that are dependent on cytoskeletal responses such as contraction, secretion, adhesion and chemotaxis. EDG receptors are developmentally regulated and differ in tissue distribution. They couple to multiple types of G proteins to signal through ras and MAP kinase, rho, phospholipase C and several protein tyrosine kinases. EDG4 is expressed in testes, ovarian tumor and leukocyte containing tissues.
Purification
Ammonium Sulfate Precipitation
Immunogène
Antibody raised against a unique synthetic peptide derived from the N-terminal of the human EDG4 protein. Antigen sequence differs in mouse and rat by one amino acid.
Isotype
IgG
Indications d'application
This antibody can be used for Western blotting (5-10 μg/mL). Western blot should be visualized using a high sensitivity secondary/substrate system (i.e. Pierce's SuperSignal West Femto Maximum Sensitivity Substrate). Optimal concentration should be evaluated by serial dilutions.
Restrictions
For Research Use only
Format
Liquid
Buffer
phosphate buffered saline with 0.08 % sodium azide
Agent conservateur
Sodium azide
Précaution d'utilisation
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Stock
-20 °C
Stockage commentaire
Product should be stored at -20°C. Aliquot to avoid freeze/thaw cycles