SUMO2 anticorps

N° du produit ABIN3032647

Cet anticorps Souris Monoclonal détecte spécifiquement SUMO2 dans WB, ELISA et IF. Il présente une réactivité avec des échantillons de Humain et Rat.

Aperçu rapide pour SUMO2 anticorps (ABIN3032647)

Antigène: SUMO2 (Small Ubiquitin Related Modifier 2 (SUMO2))

Reactivité: Humain, Rat

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp SUMO2 est non-conjugé

Application: Western Blotting (WB), ELISA, Immunofluorescence (IF)

Clone: 973CT8-1-1

Détail du produit anti-SUMO2 anticorps

Fonction: SUMO-2 Antibody

Réactivité croisée (Details): Expected species reactivity: Bovine, Chicken, Hamster, Mouse, Pig, Primate

Purification: Purified

Immunogène: Purified His-tagged protein was used to produced this monoclonal SUMO-2 antibody.

Isotype: IgG2b

Information d'application

Indications d'application: Titration of the SUMO-2 antibody may be required due to differences in protocols and secondary/substrate sensitivity.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: In 1X PBS, pH 7.4, with 0.09 % sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Aliquot the SUMO-2 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Détails sur SUMO2

Antigène: SUMO2 (Small Ubiquitin Related Modifier 2 (SUMO2))

Autre désignation: SUMO-2

Sujet: Ubiquitin-like protein that can be covalently attached to proteins as a monomer or as a lysine-linked polymer. Covalent attachment via an isopeptide bond to its substrates requires prior activation by the E1 complex SAE1-SAE2 and linkage to the E2 enzyme UBE2I, and can be promoted by an E3 ligase such as PIAS1-4, RANBP2 or CBX4. This post-translational modification on lysine residues of proteins plays a crucial role in a number of cellular processes such as nuclear transport, DNA replication and repair, mitosis and signal transduction. Polymeric SUMO2 chains are also susceptible to polyubiquitination which functions as a signal for proteasomal degradation of modified proteins.

UniProt: P61956

Pathways: Methionine Biosynthetic Process