MATK anticorps (C-Term)

N° du produit ABIN5517155

Détail du produit anti-MATK anticorps

Antigène: MATK (Megakaryocyte-Associated tyrosine Kinase (MATK))

Épitope: C-Term

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp MATK est non-conjugé

Application: Western Blotting (WB)

Séquence: SSCWEAEPAR RPPFRKLAEK LARELRSAGA PASVSGQDAD GSTSPRSQEP

Attributs du produit: This is a rabbit polyclonal antibody against MATK. It was validated on Western Blot.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the C-terminal region of Human MATK

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Détails sur MATK

Antigène: MATK (Megakaryocyte-Associated tyrosine Kinase (MATK))

Autre désignation: MATK (MATK Produits)

Synonymes: anticorps si:ch211-63j24.2, anticorps CHK, anticorps CTK, anticorps HHYLTK, anticorps HYL, anticorps HYLTK, anticorps Lsk, anticorps Ntk, anticorps Batk, anticorps megakaryocyte-associated tyrosine kinase, anticorps zinc finger RNA binding protein 2, anticorps matk, anticorps MATK, anticorps Matk, anticorps ZFR2

Sujet: The protein encoded by this gene has amino acid sequence similarity to Csk tyrosine kinase and has the structural features of the CSK subfamily: SRC homology SH2 and SH3 domains, a catalytic domain, a unique N terminus, lack of myristylation signals, lack of a negative regulatory phosphorylation site, and lack of an autophosphorylation site. This protein is thought to play a significant role in the signal transduction of hematopoietic cells. It is able to phosphorylate and inactivate Src family kinases, and may play an inhibitory role in the control of T-cell proliferation. This protein might be involved in signaling in some cases of breast cancer. Three alternatively spliced transcript variants that encode different isoforms have been described for this gene.

Alias Symbols: MATK, CTK, HYL,

Protein Interaction Partner: BRCA1, UBC, HSP90AA1, ERBB2, MYC, CACNA1A, PXN, PTK2B, NTRK1, SRC, CD36, LYN, KIT, EWSR1,

Protein Size: 507

ID gène: 4145

NCBI Accession: NP_647612

UniProt: P42679