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DHCR7 anticorps (C-Term)

DHCR7 Reactivité: Humain, Souris WB, IF, IHC (p) Hôte: Lapin Polyclonal unconjugated
N° du produit ABIN5533223
  • Antigène Voir toutes DHCR7 Anticorps
    DHCR7 (7-Dehydrocholesterol Reductase (DHCR7))
    Épitope
    • 8
    • 8
    • 6
    • 4
    • 3
    • 2
    • 2
    • 1
    • 1
    AA 437-463, C-Term
    Reactivité
    • 31
    • 28
    • 14
    Humain, Souris
    Hôte
    • 38
    • 1
    Lapin
    Clonalité
    • 38
    • 1
    Polyclonal
    Conjugué
    • 12
    • 4
    • 4
    • 4
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp DHCR7 est non-conjugé
    Application
    • 35
    • 19
    • 15
    • 14
    • 6
    • 6
    • 2
    • 1
    Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    Purification
    This antibody is purified through a protein A column, followed by peptide affinity purification.
    Immunogène
    This DHCR7 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 437-463 amino acids from the C-terminal region of human DHCR7.
    Isotype
    Ig Fraction
    Top Product
    Discover our top product DHCR7 Anticorps primaire
  • Indications d'application
    For IF starting dilution is: 1:25

    For WB starting dilution is: 1:1000

    For IHC-P starting dilution is: 1:50~100
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    0.5 mg/mL
    Buffer
    Supplied in PBS with 0.09 % (W/V) sodium azide.
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Stock
    4 °C,-20 °C
    Stockage commentaire
    Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
  • Antigène
    DHCR7 (7-Dehydrocholesterol Reductase (DHCR7))
    Autre désignation
    DHCR7 (DHCR7 Produits)
    Synonymes
    anticorps 7-Dhcr, anticorps Xdhcr7, anticorps MGC64361, anticorps slos, anticorps 7-STEROL DELTA7 REDUCTASE, anticorps 7RED, anticorps DELTA5, anticorps DWARF 5, anticorps F11F12.21, anticorps F11F12_21, anticorps LE, anticorps LEPIDA, anticorps PA, anticorps PARVA, anticorps ST7R, anticorps STEROL DELTA7 REDUCTASE, anticorps DKFZp468C1911, anticorps AA409147, anticorps SLOS, anticorps xdhcr7, anticorps 7-dehydrocholesterol reductase, anticorps 7-dehydrocholesterol reductase L homeolog, anticorps Ergosterol biosynthesis ERG4/ERG24 family, anticorps DHCR7, anticorps dhcr7, anticorps dhcr7.L, anticorps DWF5, anticorps PAAG_04766, anticorps PITG_13128, anticorps VDBG_05423, anticorps MGYG_00712, anticorps TERG_00580, anticorps Dhcr7
    Sujet
    This gene encodes an enzyme that removes the C(7-8) double bond in the B ring of sterols and catalyzes the conversion of 7-dehydrocholesterol to cholesterol. This gene is ubiquitously expressed and its transmembrane protein localizes to the endoplasmic reticulum membrane and nuclear outer membrane. Mutations in this gene cause Smith-Lemli-Opitz syndrome (SLOS), a syndrome that is metabolically characterized by reduced serum cholesterol levels and elevated serum 7-dehydrocholesterol levels and phenotypically characterized by mental retardation, facial dysmorphism, syndactyly of second and third toes, and holoprosencephaly in severe cases to minimal physical abnormalities and near-normal intelligence in mild cases. Alternative splicing results in multiple transcript variants that encode the same protein.
    Poids moléculaire
    54 kDa
    ID gène
    1717
    UniProt
    Q9UBM7
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