RRM2 anticorps (AA 1-110)

N° du produit ABIN562744

Détail du produit anti-RRM2 anticorps

Antigène: RRM2 (Ribonucleotide Reductase M2 (RRM2))

Épitope: AA 1-110

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp RRM2 est non-conjugé

Application: Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunoprecipitation (IP), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Fonction: Mouse monoclonal antibody raised against a partial recombinant RRM2.

Séquence: MLSLRVPLAP ITDPQQLQLS PLKGLSLVDK ENTPPALSGT RVLASKTARR IFQEPTEPKT KAAAPGVEDE PLLRENPRRF VIFPIEYHDI WQMYKKAEAS FWTAEEVDLS

Réactivité croisée: Humain

Attributs du produit: Antibody Reactive Against Recombinant Protein.

Immunogène: RRM2 (NP_001025, 1 a.a. ~ 110 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.

Clone: 1E1

Isotype: IgG1

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Buffer: In 1x PBS, pH 7.4

Conseil sur la manipulation: Aliquot to avoid repeated freezing and thawing.

Stock: -20 °C

Stockage commentaire: Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.

Références pour anticorps anti-RRM2 (ABIN562744)

Castelblanco, Zafon, Maravall, Gallel, Martinez, Capel, Bella, Halperin, Temprana, Iglesias, Puig-Domingo, Robledo, Matias-Guiu, Mauricio: "APLP2, RRM2, and PRC1: New Putative Markers for the Differential Diagnosis of Thyroid Follicular Lesions." dans: Thyroid : official journal of the American Thyroid Association, Vol. 27, Issue 1, pp. 59-66, (2016) (PubMed).

Kim, Park, Joo, Shen, Hong, Kim, Singh, Lee, Shin: "RRM1 maintains centrosomal integrity via CHK1 and CDK1 signaling during replication stress." dans: Cancer letters, Vol. 346, Issue 2, pp. 249-56, (2014) (PubMed).

Yoshida, Tsunoda, Doi, Tanaka, Fujimoto, Machida, Ota, Koyanagi, Takashima, Sasazuki, Kuroki, Iwasaki, Shirasawa: "KRAS-mediated up-regulation of RRM2 expression is essential for the proliferation of colorectal cancer cell lines." dans: Anticancer research, Vol. 31, Issue 7, pp. 2535-9, (2011) (PubMed).

Zhou, Snyder, Lieberman: "Epstein-Barr virus episome stability is coupled to a delay in replication timing." dans: Journal of virology, Vol. 83, Issue 5, pp. 2154-62, (2009) (PubMed).

Tang, Deng, Wang, Dai, Wang, Jiang, Li, Li, Sheng, Wu, Li, Zeng et al.: "Quantitative phosphoproteome profiling of Wnt3a-mediated signaling network: indicating the involvement of ribonucleoside-diphosphate reductase M2 subunit phosphorylation at residue serine 20 in ..." dans: Molecular & cellular proteomics : MCP, Vol. 6, Issue 11, pp. 1952-67, (2007) (PubMed).

Détails sur RRM2

Antigène: RRM2 (Ribonucleotide Reductase M2 (RRM2))

Autre désignation: RRM2 (RRM2 Produits)

Synonymes: anticorps R2, anticorps RR2, anticorps RR2M, anticorps AA407299, anticorps rrm2, anticorps rr2m, anticorps cb111, anticorps chunp6884, anticorps r2, anticorps ribonucleotide reductase regulatory subunit M2, anticorps ribonucleotide reductase M2, anticorps ribonucleotide reductase M2, gene 2 L homeolog, anticorps ribonucleotide reductase M2, gene 1, anticorps ribonucleotide reductase M2 polypeptide, anticorps RRM2, anticorps Rrm2, anticorps rrm2.2.L, anticorps rrm2.1, anticorps rrm2

Sujet: Full Gene Name: ribonucleotide reductase M2 polypeptide
Synonyms: R2,RR2M

ID gène: 6241

NCBI Accession: NM_001034

Pathways: Mitotic G1-G1/S Phases