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CTNNA2 anticorps (C-Term)

CTNNA2 Reactivité: Humain WB, ELISA, IF, ICC Hôte: Lapin Polyclonal unconjugated
N° du produit ABIN6261087
  • Antigène Voir toutes CTNNA2 Anticorps
    CTNNA2 (Catenin (Cadherin-Associated Protein), alpha 2 (CTNNA2))
    Épitope
    • 5
    • 4
    • 4
    • 1
    • 1
    C-Term
    Reactivité
    • 31
    • 14
    • 7
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    Humain
    Hôte
    • 30
    • 2
    Lapin
    Clonalité
    • 31
    Polyclonal
    Conjugué
    • 15
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    Cet anticorp CTNNA2 est non-conjugé
    Application
    • 14
    • 8
    • 4
    • 4
    • 2
    • 1
    • 1
    Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunocytochemistry (ICC)
    Specificité
    CTNNA1/CTNNA2 Antibody detects endogenous levels of total CTNNA1/CTNNA2.
    Purification
    The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
    Immunogène
    A synthesized peptide derived from human CTNNA1/CTNNA2, corresponding to a region within C-terminal amino acids.
    Isotype
    IgG
    Top Product
    Discover our top product CTNNA2 Anticorps primaire
  • Indications d'application
    WB 1:1000, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 mg/mL
    Buffer
    Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Stock
    -20 °C
    Stockage commentaire
    Store at -20 °C. Stable for 12 months from date of receipt.
    Date de péremption
    12 months
  • Antigène
    CTNNA2 (Catenin (Cadherin-Associated Protein), alpha 2 (CTNNA2))
    Autre désignation
    CTNNA1,CTNNA2 (CTNNA2 Produits)
    Synonymes
    anticorps AI481747, anticorps Catna, anticorps Catna2, anticorps cdf, anticorps chp, anticorps CAP-R, anticorps CAPR, anticorps CT114, anticorps CTNR, anticorps CTNNA1, anticorps bZ1H10.1, anticorps catna2l, anticorps im:5410539, anticorps si:rp71-1h10.1, anticorps catenin alpha 2, anticorps catenin (cadherin associated protein), alpha 2, anticorps catenin (cadherin-associated protein), alpha 2, anticorps catenin alpha 2 L homeolog, anticorps ctnna2, anticorps CTNNA2, anticorps Ctnna2, anticorps ctnna2.L
    Sujet

    Description: Associates with the cytoplasmic domain of a variety of cadherins. The association of catenins to cadherins produces a complex which is linked to the actin filament network, and which seems to be of primary importance for cadherins cell-adhesion properties. Can associate with both E- and N-cadherins. Originally believed to be a stable component of E-cadherin/catenin adhesion complexes and to mediate the linkage of cadherins to the actin cytoskeleton at adherens junctions. In contrast, cortical actin was found to be much more dynamic than E-cadherin/catenin complexes and CTNNA1 was shown not to bind to F-actin when assembled in the complex suggesting a different linkage between actin and adherens junctions components. The homodimeric form may regulate actin filament assembly and inhibit actin branching by competing with the Arp2/3 complex for binding to actin filaments. May play a crucial role in cell differentiation.

    Gene: CTNNA1

    Poids moléculaire
    100kDa
    ID gène
    1495, 1496
    UniProt
    P35221, P26232
    Pathways
    Regulation of Muscle Cell Differentiation
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