MAP2 anticorps (pSer1539)
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- Antigène Voir toutes MAP2 Anticorps
- MAP2 (Microtubule-Associated Protein 2 (MAP2))
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Épitope
- pSer1539
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Reactivité
- Humain
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp MAP2 est non-conjugé
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Application
- Dot Blot (DB)
- Homologie
- M, Rat
- Purification
- This antibody is purified through a protein A column, followed by peptide affinity purification.
- Immunogène
- This MAP2 Antibody is generated from rabbits immunized with a KLH conjugated synthetic phosphopeptide corresponding to amino acid residues surrounding S1539 of human MAP2.
- Clone
- RB15202
- Isotype
- Ig Fraction
- Top Product
- Discover our top product MAP2 Anticorps primaire
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- Indications d'application
- DB: 1:500
- Restrictions
- For Research Use only
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- Format
- Liquid
- Buffer
- Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Stock
- 4 °C,-20 °C
- Stockage commentaire
- Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
- Date de péremption
- 6 months
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- Antigène
- MAP2 (Microtubule-Associated Protein 2 (MAP2))
- Autre désignation
- MAP2 (MAP2 Produits)
- Synonymes
- anticorps MAP2A, anticorps MAP2B, anticorps MAP2C, anticorps MAP2R, anticorps Mtap2, anticorps MAP-2, anticorps Mtap-2, anticorps xmap2, anticorps MGC53131, anticorps a730034c02, anticorps zgc:103474, anticorps zgc:113974, anticorps microtubule associated protein 2, anticorps microtubule-associated protein 2, anticorps microtubule associated protein 2 S homeolog, anticorps MAP2, anticorps Map2, anticorps map2.S, anticorps map2
- Sujet
- MAP2 is the major microtubule associated protein of brain tissue. There are three forms of MAP2, two are similarily sized with apparent molecular weights of 280 kDa (MAP2a and MAP2b) and the third with a lower molecular weight of 70 kDa (MAP2c). In the newborn rat brain, MAP2b and MAP2c are present, while MAP2a is absent. Between postnatal days 10 and 20, MAP2a appears. At the same time, the level of MAP2c drops by 10-fold. This change happens during the period when dendrite growth is completed and when neurons have reached their mature morphology. MAP2 is degraded by a Cathepsin D-like protease in the brain of aged rats. There is some indication that MAP2 is expressed at higher levels in some types of neurons than in other types. MAP2 is known to promote microtubule assembly and to form side-arms on microtubules. It also interacts with neurofilaments, actin, and other elements of the cytoskeleton.
- Poids moléculaire
- 199526
- ID gène
- 4133
- NCBI Accession
- NP_001034627, NP_002365, NP_114033, NP_114035
- UniProt
- P11137
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