IGF2R anticorps (AA 2251-2300)

N° du produit ABIN6579525

Cet anticorps Lapin Polyclonal détecte spécifiquement IGF2R dans WB, ELISA et IF. Il présente une réactivité avec des échantillons de Humain, Souris et Rat.

Aperçu rapide pour IGF2R anticorps (AA 2251-2300) (ABIN6579525)

Antigène: IGF2R (Insulin-Like Growth Factor 2 Receptor (IGF2R))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp IGF2R est non-conjugé

Application: Western Blotting (WB), ELISA, Immunofluorescence (IF)

Détail du produit anti-IGF2R anticorps

Épitope: AA 2251-2300

Fonction: IGF-IIR Antibody

Specificité: IGF-IIR Polyclonal Antibody detects endogenous levels of IGF-IIR protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogène: The antiserum was produced against synthesized peptide derived from the C-terminal region of human IGF2R. AA range:2251-2300

Isotype: IgG

Information d'application

Indications d'application: WB 1:500 - 1:2000. ELISA: 1:10000.. IF 1:50-200

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C/1 year

Date de péremption: 12 months

Détails sur IGF2R

Antigène: IGF2R (Insulin-Like Growth Factor 2 Receptor (IGF2R))

Autre désignation: IGF2R

Sujet:

Synonyms: IGF2R, MPRI, Cation-independent mannose-6-phosphate receptor, CI Man-6-P receptor, CI-MPR, M6PR, 300 kDa mannose 6-phosphate receptor, MPR 300, Insulin-like growth factor 2 receptor, Insulin-like growth factor II receptor, IGF-II receptor, M6P/IGF2 receptor, M6P/IGF2R, CD222

Background: This gene encodes a receptor for both insulin-like growth factor 2 and mannose 6-phosphate. The binding sites for each ligand are located on different segments of the protein. This receptor has various functions, including in the intracellular trafficking of lysosomal enzymes, the activation of transforming growth factor beta, and the degradation of insulin-like growth factor 2. Mutation or loss of heterozygosity of this gene has been association with risk of hepatocellular carcinoma. The orthologous mouse gene is imprinted and shows exclusive expression from the maternal allele, however, imprinting of the human gene may be polymorphic, as only a minority of individuals showed biased expression from the maternal allele (PMID:8267611). [provided by RefSeq, Nov 2015],

Gene Name: IGF2R

Protein Name: Cation-independent mannose-6-phosphate receptor

Poids moléculaire: 274 kDa

ID gène: 3482

OMIM: 147280

UniProt: P11717