HIV-1 p24 anticorps

N° du produit ABIN6937461

Détail du produit anti-HIV-1 p24 anticorps

Antigène: HIV-1 p24 (Human Immunodeficiency Virus 1 Capsid (HIV-1 p24))

Reactivité: Human Immunodeficiency Virus (HIV)

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp HIV-1 p24 est non-conjugé

Application: ELISA, Immunofluorescence (IF), Immunocytochemistry (ICC), Coating (Coat)

Purification: Purified by Protein A/G

Immunogène: Recombinant HIV-1 Gag p24 protein

Clone: HIV1-24-661

Isotype: IgG1 kappa

Information d'application

Indications d'application:

Positive Control: HIV-1 infected cells. Tissues.

Known Application: ELISA (For coating, order Ab without BSA), Immunocytochemistry (Acetone or paraformaldehyde fixed) (0.5-1 μg/mL for 30 min), Immunofluorescence (0.5-1 μg/mL), Optimal dilution for a specific application should be determined.

Restrictions: For Research Use only

Stockage

Buffer: 10 mM PBS without BSA and without Azide.

Agent conservateur: Azide free

Stock: 4 °C

Stockage commentaire: Antibody with azide - store at 2 to 8°C. Antibody is stable for 24 months.

Date de péremption: 24 months

Détails sur HIV-1 p24

Antigène: HIV-1 p24 (Human Immunodeficiency Virus 1 Capsid (HIV-1 p24))

Autre désignation: Human Immunodeficiency Virus Type-1 p24 (HIV1-p24) (HIV-1 p24 Produits)

Classe de substances: Viral Protein

Sujet: Human immunodeficiency virus (HIV) is a retrovirus that causes acquired immune deficiency syndrome (AIDS), a condition in humans in which the immune system begins to fail, leading to life-threatening opportunistic infections. HIV mainly infects vital cells in the human immune system such as helper T cells (specifically CD4+ T cells), macrophages and dendritic cells. Two species of HIV infect humans: HIV-1 and HIV-2, with HIV-1 being the more virulent strain. The gag gene of human immunodeficiency virus 1 (HIV-1) encodes a precursor protein known as Pr55Gag. The viral protease PR cleaves this precursor to generate p17, p24, p7, and p6 proteins, which are required for virus particle assembly. HIV-1 Gag p24 is a capsid protein that constitutes the core of AIDS virus HIV-1. p6 and p7 are the components of the nucleocapsid, and p17 provides a protective matrix. HIV-1 Gag p24 is indispensable to the reproduction of AIDS virus and constitutes an essential element for the AIDS virus particle construction. As this protein is detectable from the early stage of AIDS virus infection, its measurement is commonly used as an indicator of HIV-1 infection and viral load.

Poids moléculaire: 24kDa (mature), 55kDa & 41kDa (precursors)

ID gène: 155348

UniProt: P04585