BMP2 anticorps (AA 283-365)

N° du produit ABIN730903

Détail du produit anti-BMP2 anticorps

Antigène: BMP2 (Bone Morphogenetic Protein 2 (BMP2))

Épitope: AA 283-365

Reactivité: Humain, Rat, Souris, Lapin, Mouton

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp BMP2 est non-conjugé

Application: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunofluorescence (Cultured Cells) (IF (cc)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Réactivité croisée: Humain, Souris, Lapin, Rat, Mouton

Homologie: Dog,Cow,Horse,Chicken

Purification: Purified by Protein A.

Immunogène: KLH conjugated synthetic peptide derived from human BMP2

Isotype: IgG

Information d'application

Indications d'application: WB 1:300-5000
ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Date de péremption: 12 months

Références pour anticorps anti-BMP2 (ABIN730903)

Wu, Jiang, Feng, Jiang, Cheng: "Negative Pressure Therapy in the Regeneration of the Sciatic Nerve Using Vacuum - Assisted Closure in a Rabbit Model." dans: Medical science monitor : international medical journal of experimental and clinical research, Vol. 24, pp. 1027-1033, (2018) (PubMed).

Zhang, Wang, Shi, Wang, Lai, Yang, Chen, Yang: "Combination of simvastatin, calcium silicate/gypsum, and gelatin and bone regeneration in rabbit calvarial defects." dans: Scientific reports, Vol. 6, pp. 23422, (2016) (PubMed).

Zhou, Yin, Jiang, Niu, Wan, Chen, Shen: "CBX7 deficiency plays a positive role in dentin and alveolar bone development." dans: Journal of molecular histology, Vol. 47, Issue 4, pp. 401-11, (2016) (PubMed).

Sari, Rufaut, Jones, Sinclair: "Characterization of Ovine Dermal Papilla Cell Aggregation." dans: International journal of trichology, Vol. 8, Issue 3, pp. 121-9, (2016) (PubMed).

Naeem, Zhu, Di, Marmiroli, OShaughnessy: "AKT1-mediated Lamin A/C degradation is required for nuclear degradation and normal epidermal terminal differentiation." dans: Cell death and differentiation, (2015) (PubMed).

Wu, Zhou, Hu, Li: "Gene expression of osteogenic factors following gene therapy in mandibular lengthening." dans: The Journal of craniofacial surgery, Vol. 26, Issue 2, pp. 378-81, (2015) (PubMed).

Kishi, Fujihara, Kawaguchi, Yamada, Nakayama, Yamamoto, Fujihara, Hamada, Satomura, Masutani: "PARP Inhibitor PJ34 Suppresses Osteogenic Differentiation in Mouse Mesenchymal Stem Cells by Modulating BMP-2 Signaling Pathway." dans: International journal of molecular sciences, Vol. 16, Issue 10, pp. 24820-38, (2015) (PubMed).

Huang, Zou, Shi, Zhang, Pen, Zhang, Gao, Wang: "The effect of electroacupuncture on the extracellular matrix synthesis and degradation in a rabbit model of disc degeneration." dans: Evidence-based complementary and alternative medicine : eCAM, Vol. 2014, pp. 731395, (2014) (PubMed).

Wu, Chen, Mi, Chen, Wang, Gao: "Expression analysis of BMP2, BMP5, BMP10 in human colon tissues from Hirschsprung disease patients." dans: International journal of clinical and experimental pathology, Vol. 7, Issue 2, pp. 529-36, (2014) (PubMed).

Wang, Bi, Zhu, Wu, Wang: "Effects of the antihypertensive drug benidipine on osteoblast function in vitro." dans: Experimental and therapeutic medicine, Vol. 7, Issue 3, pp. 649-653, (2014) (PubMed).

Lescarbeau, Seib, Prewitz, Werner, Kaplan: "In vitro model of metastasis to bone marrow mediates prostate cancer castration resistant growth through paracrine and extracellular matrix factors." dans: PLoS ONE, Vol. 7, Issue 8, pp. e40372, (2012) (PubMed).

Détails sur BMP2

Antigène: BMP2 (Bone Morphogenetic Protein 2 (BMP2))

Autre désignation: BMP2 (BMP2 Produits)

Synonymes: anticorps BDA2, anticorps BMP2A, anticorps AI467020, anticorps Bmp2a, anticorps BMP-2, anticorps xBMP-2, anticorps xbmp2, anticorps BMP2, anticorps bmp2a, anticorps bmp2, anticorps wu:fc59d09, anticorps bone morphogenetic protein 2, anticorps bone morphogenetic protein 2 L homeolog, anticorps Bone morphogenetic protein 2, anticorps bone morphogenetic protein 2a, anticorps BMP2, anticorps Bmp2, anticorps bmp2.L, anticorps bmp2, anticorps bmp2a

Sujet:

Synonyms: BDA2, BMP2A, Bone morphogenetic protein 2, BMP-2, Bone morphogenetic protein 2A, BMP-2A, BMP2

Background: BMP2 belongs to the transforming growth factor-beta (TGFB) superfamily of secreted growth factors. It is a disulfide-linked homodimer and induces bone and cartilage formation. In addition to its osteogenic activity, BMP2 plays an important role in cardiac morphogenesis and is expressed in a variety of tissues including lung, spleen, brain, liver, prostate ovary and small intestine. The functional form of BMP2 is a 26 kDa protein composed of two identical 114 amino acid polypeptide chains linked by a single disulfide bond. BMPs control fundamental events in early embryonic development, organogenesis and adult tissue homeostasis.

ID gène: 650

UniProt: P12643

Pathways: Regulation of Hormone Metabolic Process, Regulation of Hormone Biosynthetic Process, Regulation of Muscle Cell Differentiation, Growth Factor Binding, Positive Regulation of fat Cell Differentiation