ANTXR1 anticorps (AA 33-301)

N° du produit ABIN7873996

Cet anticorps anti-ANTXR1 Polyclonal Lapin (ABIN7873996) détecte spécifiquement ANTXR1 dans WB et ELISA. L’anticorps est réactif avec des échantillons de Humain, Souris et Rat.

Aperçu rapide pour ANTXR1 anticorps (AA 33-301) (ABIN7873996)

Antigène: ANTXR1 (anthrax Toxin Receptor 1 (ANTXR1))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp ANTXR1 est non-conjugé

Application: Western Blotting (WB), ELISA

Détail du produit anti-ANTXR1 anticorps

Épitope: AA 33-301

Fonction: TEM8 Antibody / Anthrax toxin receptor / ATR / ANTXR1

Purification: Antigen affinity purified

Immunogène: Recombinant human protein (amino acids E33-D301) was used as the immunogen for the TEM8 antibody.

Isotype: IgG

Information d'application

Indications d'application: Optimal dilution of the TEM8 antibody should be determined by the researcher.

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Stock: 4 °C,-20 °C

Stockage commentaire: After reconstitution, the TEM8 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

Détails sur ANTXR1

Antigène: ANTXR1 (anthrax Toxin Receptor 1 (ANTXR1))

Autre désignation: TEM8

Sujet: Anthrax toxin receptor 1 (ANTXR1 or also known as TEM8) is a protein that in humans is encoded by the ANTXR1 gene. This gene encodes a type I transmembrane protein and is a tumor-specific endothelial marker that has been implicated in colorectal cancer. The encoded protein has been shown to also be a docking protein or receptor for Bacillus anthracis toxin, the causative agent of the disease, anthrax. The binding of the protective antigen (PA) component, of the tripartite anthrax toxin, to this receptor protein mediates delivery of toxin components to the cytosol of cells. Once inside the cell, the other two components of anthrax toxin, edema factor (EF) and lethal factor (LF) disrupt normal cellular processes. Three alternatively spliced variants that encode different protein isoforms have been described.

UniProt: Q9H6X2