CNTNAP2 anticorps (AA 363-1159)

N° du produit ABIN7874334

L’anticorps anti-CNTNAP2 Polyclonal Lapin est utilisé pour la détection de CNTNAP2 dans des échantillons de Humain, Rat et Souris. Il a été validé pour WB et ELISA.

Aperçu rapide pour CNTNAP2 anticorps (AA 363-1159) (ABIN7874334)

Antigène: CNTNAP2 (Contactin Associated Protein-Like 2 (CNTNAP2))

Reactivité: Humain, Rat, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp CNTNAP2 est non-conjugé

Application: Western Blotting (WB), ELISA

Détail du produit anti-CNTNAP2 anticorps

Épitope: AA 363-1159

Fonction: CASPR2 Antibody / CNTNAP2

Purification: Antigen affinity purified

Immunogène: E. coli-derived recombinant human protein (amino acids N363-E1159) was used as the immunogen for the CASPR2 antibody.

Isotype: IgG

Information d'application

Indications d'application: Optimal dilution of the CASPR2 antibody should be determined by the researcher.

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Stock: 4 °C,-20 °C

Stockage commentaire: After reconstitution, the CASPR2 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

Détails sur CNTNAP2

Antigène: CNTNAP2 (Contactin Associated Protein-Like 2 (CNTNAP2))

Autre désignation: CASPR2

Sujet: Contactin-associated protein-like 2 is a protein that in humans is encoded by the CNTNAP2 gene. This gene encodes a member of the neurexin family which functions in the vertebrate nervous system as cell adhesion molecules and receptors. This protein, like other neurexin proteins, contains epidermal growth factor repeats and laminin G domains. In addition, it includes an F5/8 type C domain, discoidin/neuropilin- and fibrinogen-like domains, thrombospondin N-terminal-like domains and a putative PDZ binding site. This protein is localized at the juxtaparanodes of myelinated axons, and mediates interactions between neurons and glia during nervous system development and is also involved in localization of potassium channels within differentiating axons. This gene encompasses almost 1.5 % of chromosome 7 and is one of the largest genes in the human genome. It is directly bound and regulated by forkhead box protein P2, a transcription factor related to speech and language development. This gene has been implicated in multiple neurodevelopmental disorders, including Gilles de la Tourette syndrome, schizophrenia, epilepsy, autism, ADHD and intellectual disability.

UniProt: Q9UHC6