IGF2R anticorps (AA 424-529)

N° du produit ABIN7874935

Cet anticorps anti-IGF2R Monoclonal Souris (Clone 4I11) (ABIN7874935) détecte spécifiquement IGF2R dans WB, FACS, IF et IHC (p). L’anticorps est réactif avec des échantillons de Humain.

Aperçu rapide pour IGF2R anticorps (AA 424-529) (ABIN7874935)

Antigène: IGF2R (Insulin-Like Growth Factor 2 Receptor (IGF2R))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp IGF2R est non-conjugé

Application: Western Blotting (WB), Flow Cytometry (FACS), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Clone: 4I11

Détail du produit anti-IGF2R anticorps

Épitope: AA 424-529

Fonction: IGF2R Antibody / M6PR

Purification: Affinity purified

Immunogène: An E. coli-derived human protein (amino acids F424-R529) was used as the immunogen for the IGF2R antibody.

Isotype: IgG2a

Information d'application

Indications d'application: Optimal dilution of the IGF2R antibody should be determined by the researcher.

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Stock: 4 °C,-20 °C

Stockage commentaire: After reconstitution, the IGF2R antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

Détails sur IGF2R

Antigène: IGF2R (Insulin-Like Growth Factor 2 Receptor (IGF2R))

Autre désignation: IGF2R

Sujet: Insulin-like growth factor 2 receptor, also called IGF2R or I-MPR is a protein that in humans is encoded by the IGF2R gene. This gene is mapped to 6q25.3. This gene encodes a receptor for both insulin-like growth factor 2 and mannose 6-phosphate, although the binding sites for either are located on different segments of the receptor. This receptor functions in the intracellular trafficking of lysosomal enzymes, the activation of transforming growth factor beta, and the degradation of insulin-like growth factor 2. While the related mouse gene shows exclusive expression from the maternal allele, imprinting of the human gene appears to be polymorphic, with only a minority of individuals showing expression from the maternal allele.

UniProt: P11717