M6PR anticorps (AA 424-529)

N° du produit ABIN7874936

Cet anticorps Souris Monoclonal détecte spécifiquement M6PR dans WB et IHC (p). Il présente une réactivité avec des échantillons de Humain.

Aperçu rapide pour M6PR anticorps (AA 424-529) (ABIN7874936)

Antigène: M6PR (Mannose-6-Phosphate Receptor (Cation Dependent) (M6PR))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp M6PR est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Clone: 6G2

Détail du produit anti-M6PR anticorps

Épitope: AA 424-529

Fonction: M6PR Antibody / IGF2R

Purification: Affinity purified

Immunogène: An E. coli-derived human protein (amino acids F424-R529) was used as the immunogen for the M6PR antibody.

Isotype: IgG2b

Information d'application

Indications d'application: Optimal dilution of the M6PR antibody should be determined by the researcher.

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Stock: 4 °C,-20 °C

Stockage commentaire: After reconstitution, the M6PR antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

Détails sur M6PR

Antigène: M6PR (Mannose-6-Phosphate Receptor (Cation Dependent) (M6PR))

Autre désignation: M6PR

Sujet: Insulin-like growth factor 2 receptor, also called IGF2R or I-MPR is a protein that in humans is encoded by the IGF2R gene. This gene is mapped to 6q25.3. This gene encodes a receptor for both insulin-like growth factor 2 and mannose 6-phosphate, although the binding sites for either are located on different segments of the receptor. This receptor functions in the intracellular trafficking of lysosomal enzymes, the activation of transforming growth factor beta, and the degradation of insulin-like growth factor 2. While the related mouse gene shows exclusive expression from the maternal allele, imprinting of the human gene appears to be polymorphic, with only a minority of individuals showing expression from the maternal allele.

UniProt: P11717