SPOP-B anticorps
Aperçu rapide pour SPOP-B anticorps (ABIN7882341)
Antigène
Voir toutes SPOP-B AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Fonction
- SPOP Antibody / Speckle-type POZ protein
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Séquence
- LHSADQLKTQ AVDFINYHAS DVLE
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Purification
- Antigen affinity purified
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Immunogène
- Amino acids LHSADQLKTQAVDFINYHASDVLE from the human protein were used as the immunogen for the SPOP antibody.
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Isotype
- IgG
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Indications d'application
- Optimal dilution of the SPOP antibody should be determined by the researcher.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Buffer
- 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water
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Stock
- 4 °C,-20 °C
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Stockage commentaire
- After reconstitution, the SPOP antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.
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- SPOP-B (Speckle-Type POZ Protein (SPOP-B))
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Autre désignation
- SPOP
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Sujet
- Speckle-type POZ protein is a protein that in humans is encoded by the SPOP gene. This gene encodes a protein that may modulate the transcriptional repression activities of death-associated protein 6 (DAXX), which interacts with histone deacetylase, core histones, and other histone-associated proteins. In mouse, the encoded protein binds to the putative leucine zipper domain of macroH2A1.2, a variant H2A histone that is enriched on inactivated X chromosomes. The BTB/POZ domain of this protein has been shown in other proteins to mediate transcriptional repression and to interact with components of histone deacetylase co-repressor complexes. Alternative splicing of this gene results in multiple transcript variants encoding the same protein.
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UniProt
- O43791
Antigène
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