TYMS anticorps

N° du produit ABIN7882469

Cet anticorps anti-TYMS Monoclonal Lapin (Clone ADAA-20) (ABIN7882469) détecte spécifiquement TYMS dans WB. L’anticorps est réactif avec des échantillons de Humain, Souris, Rat et Singe.

Aperçu rapide pour TYMS anticorps (ABIN7882469)

Antigène: TYMS (Thymidylate Synthetase (TYMS))

Reactivité: Humain, Souris, Rat, Singe

Hôte: Lapin

Clonalité: Monoclonal

Conjugué: Cet anticorp TYMS est non-conjugé

Application: Western Blotting (WB)

Clone: ADAA-20

Détail du produit anti-TYMS anticorps

Fonction: Thymidylate Synthase Antibody

Purification: Affinity purified

Immunogène: A synthetic peptide specific to human Thymidylate Synthase / TYMS was used as the immunogen for the Thymidylate Synthase antibody.

Isotype: IgG

Information d'application

Indications d'application: Optimal dilution of the Thymidylate Synthase antibody should be determined by the researcher.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Antibody in PBS with 0.02 % sodium azide, 50 % glycerol and 0.4-0.5 mg/mL BSA

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store the Thymidylate Synthase antibody at -20oC.

Détails sur TYMS

Antigène: TYMS (Thymidylate Synthetase (TYMS))

Autre désignation: Thymidylate Synthase

Sujet: Thymidylate synthase catalyzes the methylation of deoxyuridylate to deoxythymidylate using, 10-methylenetetrahydrofolate (methylene-THF) as a cofactor. This function maintains the dTMP (thymidine-5-prime monophosphate) pool critical for DNA replication and repair. The enzyme has been of interest as a target for cancer chemotherapeutic agents. It is considered to be the primary site of action for 5-fluorouracil, 5-fluoro-2-prime-deoxyuridine, and some folate analogs. Expression of this gene and that of a naturally occurring antisense transcript, mitochondrial enolase superfamily member 1, vary inversely when cell-growth progresses from late-log to plateau phase. Polymorphisms in this gene may be associated with etiology of neoplasia, including breast cancer, and response to chemotherapy. [RefSeq]

UniProt: P04818

Pathways: Mitotic G1-G1/S Phases