GBP1 anticorps (C-Term) (PE)

N° du produit ABIN7995842

Cet anticorps anti-GBP1 Polyclonal Lapin conjugué à PE (ABIN7995842) détecte spécifiquement GBP1 dans FACS. L’anticorps est réactif avec des échantillons de Humain.

Aperçu rapide pour GBP1 anticorps (C-Term) (PE) (ABIN7995842)

Antigène: GBP1 (Guanylate Binding Protein 1, Interferon-Inducible (GBP1))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp GBP1 est conjugé à/à la PE

Application: Flow Cytometry (FACS)

Détail du produit anti-GBP1 anticorps (PE)

Épitope: C-Term

Fonction: Anti-Guanylate-binding protein 1 GBP1 Antibody PE Conjugated

Specificité: No cross reactivity with other proteins.

Réactivité croisée (Details): No cross-reactivity with other proteins

Purification: Immunogen affinity purified.

Immunogène: A synthetic peptide corresponding to a sequence at the C-terminus of human GBP1.

Isotype: IgG

Information d'application

Indications d'application: Flow Cytometry, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Date de péremption: 12 months

Détails sur GBP1

Antigène: GBP1 (Guanylate Binding Protein 1, Interferon-Inducible (GBP1))

Autre désignation: GBP1

Sujet:

Background: Interferons induce a large number of genes in their target cells, including those coding for guanylate-binding proteins (GBPs). GBPs, such as GBP1, are characterized by their ability to specifically bind guanine nucleotides (GMP, GDP, and GTP) and are distinguished from the GTP-binding proteins by the presence of 2 binding motifs rather than 3. The 593-amino acid GBP1 protein shares 77 % and 88 % identity with GBP2 and GBP3, respectively. All GBPs, including GBP1, have a conserved N-terminal globular GTP-binding domain containing 2 consensus sequences and a third T (L/V)RD sequence not found in other GTPases. The GBP1 gene to the GBP gene cluster on chromosome 1p22.2. It is located telomeric to GBP2 and centromeric to GBP3. High expression of GBP1, GBP2, and GBP3 are in endothelial cells after stimulation with IFNG, TNF, or IL1B .

Gene Full Name: guanylate binding protein 1

Sequence Similarities: Belongs to the TRAFAC class dynamin-like GTPase superfamily. GB1/RHD3-type GTPase family. GB1 subfamily.

ID gène: 2633

UniProt: P32455

Pathways: Cellular Response to Molecule of Bacterial Origin