HEXB anticorps (AA 381-556) (PE)

N° du produit ABIN7997516

Cet anticorps anti-HEXB Polyclonal Lapin conjugué à PE (ABIN7997516) détecte spécifiquement HEXB dans FACS. L’anticorps est réactif avec des échantillons de Humain.

Aperçu rapide pour HEXB anticorps (AA 381-556) (PE) (ABIN7997516)

Antigène: HEXB (Hexosaminidase B (Beta Polypeptide) (HEXB))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp HEXB est conjugé à/à la PE

Application: Flow Cytometry (FACS)

Détail du produit anti-HEXB anticorps (PE)

Épitope: AA 381-556

Fonction: Anti-HEXB Antibody PE Conjugated

Specificité: No cross reactivity with other proteins.

Réactivité croisée (Details): No cross-reactivity with other proteins

Homologie: Human HEXB shares 75%,73% amino acid (aa) sequences identity with mouse,rat HEXB,respectively.

Purification: Immunogen affinity purified.

Immunogène: E.coli-derived human HEXB recombinant protein (Position: K381-M556). Human HEXB shares 75% and 73% amino acid (aa) sequences identity with mouse and rat HEXB, respectively.

Isotype: IgG

Information d'application

Indications d'application: Flow Cytometry, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Date de péremption: 12 months

Détails sur HEXB

Antigène: HEXB (Hexosaminidase B (Beta Polypeptide) (HEXB))

Autre désignation: HEXB

Sujet:

Background: Beta-hexosaminidase subunit beta (HEXB) is an enzyme that in humans is encoded by the HEXB gene. It is mapped to 5q13.3. HEXB is the beta subunit of the lysosomal enzyme beta-hexosaminidase that, together with the cofactor GM2 activator protein, catalyzes the degradation of the ganglioside GM2, and other molecules containing terminal N-acetyl hexosamines. Beta subunit gene mutations lead to Sandhoff disease (GM2-gangliosidosis type II). It has been found that HEXB is a peptidoglycan hydrolase and it is involved in restricting mycobacteria growth even before the onset of adaptive immunity.

Gene Full Name: hexosaminidase subunit beta

Sequence Similarities: Belongs to the glycosyl hydrolase 20 family.

ID gène: 3074

UniProt: P07686

Pathways: Sensory Perception of Sound, Glycosaminoglycan Metabolic Process