HEXB anticorps (AA 381-556)

N° du produit ABIN7997518

L’anticorps anti-HEXB Polyclonal Lapin est utilisé pour la détection de HEXB dans des échantillons de Humain. Il a été validé pour WB et IHC.

Aperçu rapide pour HEXB anticorps (AA 381-556) (ABIN7997518)

Antigène: HEXB (Hexosaminidase B (Beta Polypeptide) (HEXB))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp HEXB est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Classe de qualité: Carrier-free

Détail du produit anti-HEXB anticorps

Épitope: AA 381-556

Fonction: Anti-HEXB Antibody

Specificité: No cross reactivity with other proteins.

Réactivité croisée (Details): No cross-reactivity with other proteins

Homologie: Human HEXB shares 75%,73% amino acid (aa) sequences identity with mouse,rat HEXB,respectively.

Attributs du produit: Anti-HEXB Antibody. Tested in IHC, WB applications. This antibody reacts with Human.

Purification: Immunogen affinity purified.

Immunogène: E.coli-derived human HEXB recombinant protein (Position: K381-M556). Human HEXB shares 75% and 73% amino acid (aa) sequences identity with mouse and rat HEXB, respectively.

Isotype: IgG

Information d'application

Indications d'application: Immunohistochemistry (Paraffin-embedded Section), 0.5-1 μg/mL, HumanWestern blot, 0.1-0.5 μg/mL, Human

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Concentration: 500 μg/mL

Buffer: Each vial contains antibody formulated with stabilizing components, 0.9 mg NaCl, 0.2 mg Na2HPO4, and 0.05 mg Sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.

Date de péremption: 12 months

Détails sur HEXB

Antigène: HEXB (Hexosaminidase B (Beta Polypeptide) (HEXB))

Autre désignation: HEXB

Sujet:

Background: Beta-hexosaminidase subunit beta (HEXB) is an enzyme that in humans is encoded by the HEXB gene. It is mapped to 5q13.3. HEXB is the beta subunit of the lysosomal enzyme beta-hexosaminidase that, together with the cofactor GM2 activator protein, catalyzes the degradation of the ganglioside GM2, and other molecules containing terminal N-acetyl hexosamines. Beta subunit gene mutations lead to Sandhoff disease (GM2-gangliosidosis type II). It has been found that HEXB is a peptidoglycan hydrolase and it is involved in restricting mycobacteria growth even before the onset of adaptive immunity.

Gene Full Name: hexosaminidase subunit beta

Sequence Similarities: Belongs to the glycosyl hydrolase 20 family.

Poids moléculaire: 63 kDa

ID gène: 3074

UniProt: P07686

Pathways: Sensory Perception of Sound, Glycosaminoglycan Metabolic Process