MATK anticorps (AA 18-298) (Cy3)

N° du produit ABIN8008782

L’anticorps anti-MATK Polyclonal Lapin est utilisé pour la détection de MATK dans des échantillons de Humain, Souris et Rat. Il a été validé pour FACS.

Aperçu rapide pour MATK anticorps (AA 18-298) (Cy3) (ABIN8008782)

Antigène: MATK (Megakaryocyte-Associated tyrosine Kinase (MATK))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp MATK est conjugé à/à la Cy3

Application: Flow Cytometry (FACS)

Détail du produit anti-MATK anticorps (Cy3)

Épitope: AA 18-298

Fonction: Anti-MATK Antibody Cy3 Conjugated

Homologie: Human MATK shares 88.5%,91.4% amino acid (aa) sequence identity with mouse,rat MATK,respectively.

Purification: Immunogen affinity purified.

Immunogène: E.coli-derived human MATK recombinant protein (Position: S18-Q298). Human MATK shares 88.5% and 91.4% amino acid (aa) sequence identity with mouse and rat MATK, respectively.

Isotype: IgG

Information d'application

Indications d'application: Flow Cytometry, 1-3 μg/1x10⁶ cells

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Date de péremption: 12 months

Détails sur MATK

Antigène: MATK (Megakaryocyte-Associated tyrosine Kinase (MATK))

Autre désignation: MATK

Sujet:

Background: Megakaryocyte-associated tyrosine-protein kinase is an enzyme that in humans is encoded by the MATK gene. The protein encoded by this gene has amino acid sequence similarity to Csk tyrosine kinase and has the structural features of the CSK subfamily: SRC homology SH2 and SH3 domains, a catalytic domain, a unique N terminus, lack of myristylation signals, lack of a negative regulatory phosphorylation site, and lack of an autophosphorylation site. This protein is thought to play a significant role in the signal transduction of hematopoietic cells. It is able to phosphorylate and inactivate Src family kinases, and may play an inhibitory role in the control of T-cell proliferation. This protein might be involved in signaling in some cases of breast cancer. Three alternatively spliced transcript variants that encode different isoforms have been described for this gene.

Gene Full Name: megakaryocyte-associated tyrosine kinase

ID gène: 4145

UniProt: P42679