SECISBP2 anticorps (AA 12-854) (Fluoro488)

N° du produit ABIN8035045

Cet anticorps anti-SECISBP2 Polyclonal Lapin conjugué à Fluoro488 (ABIN8035045) détecte spécifiquement SECISBP2 dans FACS. L’anticorps est réactif avec des échantillons de Humain.

Aperçu rapide pour SECISBP2 anticorps (AA 12-854) (Fluoro488) (ABIN8035045)

Antigène: SECISBP2 (SECIS Binding Protein 2 (SECISBP2))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp SECISBP2 est conjugé à/à la Fluoro488

Application: Flow Cytometry (FACS)

Détail du produit anti-SECISBP2 anticorps (Fluoro488)

Épitope: AA 12-854

Fonction: Anti-SECISBP2 Antibody Fluoro488 Conjugated

Réactivité croisée (Details): No cross reactivity with other proteins.

Homologie: Human SECISBP2 shares 71.7% amino acid (aa) sequence identity with rat SECISBP2.

Purification: Immunogen affinity purified.

Immunogène: E.coli-derived human SECISBP2 recombinant protein (Position: E12-L854). Human SECISBP2 shares 71.7% amino acid (aa) sequence identity with rat SECISBP2.

Isotype: IgG

Information d'application

Indications d'application: Flow Cytometry, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Date de péremption: 12 months

Détails sur SECISBP2

Antigène: SECISBP2 (SECIS Binding Protein 2 (SECISBP2))

Autre désignation: SECISBP2

Sujet:

Background: SECIS-binding protein 2 (commonly referred to as SBP2) is a protein that in humans is encoded by the SECISBP2 gene. The protein encoded by this gene is one of the essential components of the machinery involved in co-translational insertion of selenocysteine (Sec) into selenoproteins. Sec is encoded by the UGA codon, which normally signals translation termination. The recoding of UGA as Sec codon requires a Sec insertion sequence (SECIS) element, present in the 3' untranslated regions of eukaryotic selenoprotein mRNAs. This protein specifically binds to the SECIS element, which is stimulated by a Sec-specific translation elongation factor. Mutations in this gene have been associated with reduction in enzymatic activity of type II iodothyronine deiodinase (a selenoprotein) and abnormal thyroid hormone metabolism. Alternatively spliced transcript variants have been found for this gene.

Gene Full Name: SECIS binding protein 2

ID gène: 79048

UniProt: Q96T21