SECISBP2 anticorps (AA 12-854)

N° du produit ABIN8035053

L’anticorps anti-SECISBP2 Polyclonal Lapin est utilisé pour la détection de SECISBP2 dans des échantillons de Humain. Il a été validé pour WB, ELISA, IF et ICC.

Aperçu rapide pour SECISBP2 anticorps (AA 12-854) (ABIN8035053)

Antigène: SECISBP2 (SECIS Binding Protein 2 (SECISBP2))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp SECISBP2 est non-conjugé

Application: Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunocytochemistry (ICC)

Classe de qualité: Carrier-free

Détail du produit anti-SECISBP2 anticorps

Épitope: AA 12-854

Fonction: Anti-SECISBP2 Antibody

Réactivité croisée (Details): No cross reactivity with other proteins.

Homologie: Human SECISBP2 shares 71.7% amino acid (aa) sequence identity with rat SECISBP2.

Attributs du produit: Anti-SECISBP2 Antibody. Tested in WB, ICC/IF, ELISA applications. This antibody reacts with Human.

Purification: Immunogen affinity purified.

Immunogène: E.coli-derived human SECISBP2 recombinant protein (Position: E12-L854). Human SECISBP2 shares 71.7% amino acid (aa) sequence identity with rat SECISBP2.

Isotype: IgG

Information d'application

Indications d'application: Western blot, 0.25-0.5 μg/mL, Human Immunocytochemistry/Immunofluorescence, 5 μg/mL, Human ELISA, 0.1-0.5 μg/mL, -

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Concentration: 500 μg/mL

Buffer: Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.

Stock: 4 °C,-20 °C

Stockage commentaire: At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.

Date de péremption: 12 months

Détails sur SECISBP2

Antigène: SECISBP2 (SECIS Binding Protein 2 (SECISBP2))

Autre désignation: SECISBP2

Sujet:

Background: SECIS-binding protein 2 (commonly referred to as SBP2) is a protein that in humans is encoded by the SECISBP2 gene. The protein encoded by this gene is one of the essential components of the machinery involved in co-translational insertion of selenocysteine (Sec) into selenoproteins. Sec is encoded by the UGA codon, which normally signals translation termination. The recoding of UGA as Sec codon requires a Sec insertion sequence (SECIS) element, present in the 3' untranslated regions of eukaryotic selenoprotein mRNAs. This protein specifically binds to the SECIS element, which is stimulated by a Sec-specific translation elongation factor. Mutations in this gene have been associated with reduction in enzymatic activity of type II iodothyronine deiodinase (a selenoprotein) and abnormal thyroid hormone metabolism. Alternatively spliced transcript variants have been found for this gene.

Gene Full Name: SECIS binding protein 2

Poids moléculaire: 105 kDa

ID gène: 79048

UniProt: Q96T21