CHD3 anticorps (C-Term)

N° du produit ABIN8097021

Cet anticorps anti-CHD3 Polyclonal Lapin (ABIN8097021) détecte spécifiquement CHD3 dans WB. L’anticorps est réactif avec des échantillons de Humain.

Aperçu rapide pour CHD3 anticorps (C-Term) (ABIN8097021)

Antigène: CHD3 (Chromodomain Helicase DNA Binding Protein 3 (CHD3))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp CHD3 est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-CHD3 anticorps

Épitope: C-Term

Fonction: CHD3 Antibody - C-terminal region

Séquence: RKKRDSEEEF GSERDEYREK SESGGSEYGT GPGRKRRRKH REKKEKKTKR

Homologie: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%

Purification: Affinity purified

Immunogène: The immunogen is a synthetic peptide directed towards the C terminal region of human CHD3

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Commentaires:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP32459-100UG

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: prevent freeze-thaw cycles

Stock: 4 °C,-20 °C

Stockage commentaire: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Détails sur CHD3

Antigène: CHD3 (Chromodomain Helicase DNA Binding Protein 3 (CHD3))

Autre désignation: CHD3

Sujet:

Background Information: This gene encodes a member of the CHD family of proteins which are characterized by the presence of chromo (chromatin organization modifier) domains and SNF2-related helicase/ATPase domains. This protein is one of the components of a histone deacetylase complex referred to as the Mi-2/NuRD complex which participates in the remodeling of chromatin by deacetylating histones. Chromatin remodeling is essential for many processes including transcription. Autoantibodies against this protein are found in a subset of patients with dermatomyositis. Three alternatively spliced transcripts encoding different isoforms have been described.

Gene Name: chromodomain helicase DNA binding protein 3

Alternative Symbols: ZFH, Mi-2a, SNIBCPS, Mi2-ALPHA

Protein Name: Chromodomain-helicase-DNA-binding protein 3

Poids moléculaire: 220 kDa

ID gène: 1107

NCBI Accession: NP_005843

UniProt: Q12873