gamma 1 Adaptin anticorps (AA 646-659)
Aperçu rapide pour gamma 1 Adaptin anticorps (AA 646-659) (ABIN401169)
Antigène
Voir toutes gamma 1 Adaptin (AP1G1) AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- AA 646-659
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Specificité
- This antibody is directed against AP1G1.
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Réactivité croisée (Details)
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Species reactivity (expected):Chimpanzee, Orangutan, Mouse, Rat, Canine, Chicken.
Species reactivity (tested):Human. -
Purification
- Affinity chromatography
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Immunogène
- Synthetic peptide corresponding aa 646-659 of Human AP1G1
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Isotype
- IgG
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Indications d'application
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ELISA: 1/2,000 - 1/8,000. Western Blot: 1/500 - 1/2,000.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
Restrictions
- For Research Use only
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Concentration
- 0.7 mg/mL (by UV absorbance at 280 nm)
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Buffer
- 0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2 containing 0.01 % (w/v) Sodium Azide
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Conseil sur la manipulation
- Avoid repeated freezing and thawing.
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Stock
- -20 °C
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- gamma 1 Adaptin (AP1G1) (Adaptor-Related Protein Complex 1, gamma 1 Subunit (AP1G1))
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Autre désignation
- AP1 Complex Subunit gamma-1
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Sujet
- AP1G1 (also known as gamma 1 subunit of adaptor -related protein complex 1, Gammaadaptin, Adaptor protein complex AP-1 gamma-1 subunit, Golgi adaptor HA1/AP1 adaptin gamma-1 subunit and Clathrin assembly protein complex 1 gamma-1 large chain) is a subunit of clathrin-associated adaptor protein complex 1 that plays a role in protein sorting in the late- Golgi/trans-Golgi network (TGN) and/or endosomes. The AP complexes mediate both the recruitment of clathrin to membranes and the recognition of sorting signals within the cytosolic tails of transmembrane cargo molecules. The adaptin family of proteins is composed of four classes of molecules named alpha, beta-, beta prime- and gamma- adaptins. Adaptins, together with medium and small subunits, form a heterotetrameric complex called an adaptor, whose role is to promote the formation of clathrin-coated pits and vesicles. AP1G1 is localized to the coat surrounding the cytoplasmic face of coated vesicles located at the Golgi complex and is widely expressed.Synonyms: ADTG, AP1G1, Adapter-related protein complex 1 subunit gamma-1, Adaptor protein complex AP-1 subunit gamma-1, CLAPG1, Clathrin assembly protein complex 1 gamma-1 large chain, Golgi adaptor HA1/AP1, gamma 1 Adaptin, gamma Adaptin
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ID gène
- 164
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NCBI Accession
- NP_001025178
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UniProt
- O43747
Antigène
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