GRM2 anticorps (Internal Region)
Aperçu rapide pour GRM2 anticorps (Internal Region) (ABIN569585)
Antigène
Voir toutes GRM2 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- Internal Region
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Séquence
- C-KETAPERREV
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Specificité
- This antibody is expected to recognize both isoforms of GRM2 (NP_000830.2 and NP_001123535.1).
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Réactivité croisée (Details)
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Species reactivity (expected):Mouse, Rat, Canine (Dog), Bovine, Rabbit.
Species reactivity (tested):Human. -
Purification
- Ammonium Sulphate Precipitation followed by Antigen Affinity Chromatography using the immunizing peptide
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Immunogène
- Peptide with sequence from the internal region of Human GRM2 (NP_000830.2, NP_001123535.1). Genename: GRM2
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Indications d'application
- Optimal working dilution should be determined by the investigator.
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Restrictions
- For Research Use only
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Concentration
- 0.5 mg/mL
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Buffer
- Tris saline, pH ~7.3, 0.02 % Sodium Azide, 0.5 % BSA
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Conseil sur la manipulation
- Avoid repeated freezing and thawing.
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Stock
- 4 °C/-20 °C
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Stockage commentaire
- Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
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- GRM2 (Glutamate Receptor, Metabotropic 2 (GRM2))
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Autre désignation
- mGluR2 / GRM2
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Sujet
- The Metabotropic Glutamate Receptor GRM2 binds L-glutamate and has been linked to the inhibition of the cyclic AMP signaling cascade. GRM2 is involved in mediating the suppression of neurotransmission and in synaptogenesis and synaptic stabilization. Glutamatergic neurotransmission plays a role in most aspects of normal brain function and can be perturbed in many neuropathologic conditions.Synonyms: GPRC1B, Metabotropic glutamate receptor 2
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ID gène
- 2912
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NCBI Accession
- NP_000830
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UniProt
- Q14416
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Pathways
- cAMP Metabolic Process, Dicarboxylic Acid Transport
Antigène
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