ABCC4 anticorps (C-Term)
Aperçu rapide pour ABCC4 anticorps (C-Term) (ABIN185302)
Antigène
Voir toutes ABCC4 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
Classe de qualité
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Épitope
- C-Term
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Fonction
- ABCC4 / MRP4
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Séquence
- CNGQPSTLTI FETAL
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Specificité
- This antibody is expected to recognize isoform 1 (NP_005836.2) only.
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Réactivité croisée
- Humain, Souris, Rat
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Purification
- Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
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Immunogène
- Peptide with sequence CNGQPSTLTIFETAL, from the C Terminus of the protein sequence according to NP_005836.2.
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Isotype
- IgG
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Indications d'application
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Immunohistochemistry: In paraffin embedded Human Prostate shows membranous staining in the secretory cells. Recommended concentration, 4-6 μg/mL.
Peptide ELISA: antibody detection limit dilution 1:32000.
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 0.5 mg/mL
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Buffer
- Supplied at 0.5 mg/mL in Tris saline, 0.02 % sodium azide, pH 7.3 with 0.5 % bovine serum albumin.
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Conseil sur la manipulation
- Minimize freezing and thawing.
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Stock
- -20 °C
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Stockage commentaire
- Aliquot and store at -20°C, with minimal freeze/thawing. A working aliquot may be refrigerated at 4°C for a few weeks and still remain viable.
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: "Augmented epithelial multidrug resistance-associated protein 4 expression in peritoneal endometriosis: regulation by lipoxin A(4)." dans: Fertility and sterility, Vol. 99, Issue 7, pp. 1965-73.e2, (2013) (PubMed).
: "Multidrug resistance protein 4 (MRP4) expression in prostate cancer is associated with androgen signaling and decreases with tumor progression." dans: Virchows Archiv : an international journal of pathology, Vol. 462, Issue 4, pp. 437-43, (2013) (PubMed).
: "Nuclear factor-E2-related factor 2 is a major determinant of bile acid homeostasis in the liver and intestine." dans: American journal of physiology. Gastrointestinal and liver physiology, Vol. 302, Issue 9, pp. G925-36, (2012) (PubMed).
: "Aryl hydrocarbon receptor and NF-E2-related factor 2 are key regulators of human MRP4 expression." dans: American journal of physiology. Gastrointestinal and liver physiology, Vol. 299, Issue 1, pp. G126-35, (2010) (PubMed).
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- ABCC4 (ATP-Binding Cassette, Sub-Family C (CFTR/MRP), Member 4 (ABCC4))
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Autre désignation
- ABCC4
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Sujet
- ABCC4, MRP4, MOATB, MOAT-B, EST170205, ATP-binding cassette, sub-family C (CFTR/MRP), member 4, canalicular multispecific organic anion transporter (ABC superfamily), Multidrug Resistance Protein 4, RP11-74A12.1, ATP-binding cassette, sub-family C, member
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Poids moléculaire
- 149kDa
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ID gène
- 10257, 170924
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NCBI Accession
- NP_005836
Antigène
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