AKR1C3 anticorps (AA 311-323)
Aperçu rapide pour AKR1C3 anticorps (AA 311-323) (ABIN343889)
Antigène
Voir toutes AKR1C3 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- AA 311-323
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Specificité
- Human AKR1C3.
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Homologie
- Percent identity with other species by BLAST analysis: Human (100%), Gorilla (92%), Orangutan (92%), Gibbon (92%), Monkey (92%).
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Purification
- Immunoaffinity purified
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Immunogène
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Synthetic peptide C-FASHPNYPYSDEY from the C-terminus of human AKR1C3 (NP_003730.4). Percent identity with other species by BLAST analysis: Human (100%), Gorilla (92%), Orangutan (92%), Gibbon (92%), Monkey (92%).
Type of Immunogen: Synthetic peptide
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Indications d'application
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Approved: IHC, IHC-P (5 μg/mL), Peptide-ELISA (1:32000), WB (1:32000, 0.01 - 0.1 μg/mL)
Usage: Immunohistochemistry: This antibody was validated for use in immunohistochemistry on a panel of 21 formalin-fixed, paraffin-embedded (FFPE) human tissues after heat induced antigen retrieval in pH 6.0 citrate buffer. After incubation with the primary antibody, slides were incubated with biotinylated secondary antibody, followed by alkaline phosphatase-streptavidin and chromogen. The stained slides were evaluated by a pathologist to confirm staining specificity. The optimal working concentration for this antibody was determined to be 5 μg/mL. -
Commentaires
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Target Species of Antibody: Human
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- Lot specific
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Buffer
- Tris-buffered saline, pH 7.3, 0.5 % BSA, 0.02 % sodium azide
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Conseil sur la manipulation
- Minimize freezing and thawing.
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Stock
- -20 °C
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Stockage commentaire
- Store at -20°C. Avoid freeze-thaw cycles.
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- AKR1C3 (Aldo-Keto Reductase Family 1, Member C3 (3-alpha Hydroxysteroid Dehydrogenase, Type II) (AKR1C3))
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Autre désignation
- DDX / AKR1C3
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Sujet
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Name/Gene ID: AKR1C3
Synonyms: AKR1C3, 3-alpha-HSD type 2, 17-beta-HSD 5, 3-alpha-HSD type II, brain, DD3, DDH1, DDX, Dihydrodiol dehydrogenase 3, Dihydrodiol dehydrogenase X, DD-3, HA1753, HAKRe, HAKRB, HSD17B5, KIAA0119, Kia0119, Prostaglandin F synthase, PGFS, Truncated aldoketo reductase a, HluPGFS, Indanol dehydrogenase -
ID gène
- 8644
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NCBI Accession
- NP_003730
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UniProt
- P42330
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Pathways
- Retinoic Acid Receptor Signaling Pathway, Steroid Hormone Biosynthesis, Regulation of Hormone Metabolic Process, Regulation of Hormone Biosynthetic Process, C21-Steroid Hormone Metabolic Process, Protein targeting to Nucleus
Antigène
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