Smooth Muscle Actin anticorps (N-Term)
Aperçu rapide pour Smooth Muscle Actin anticorps (N-Term) (ABIN356281)
Antigène
Voir toutes Smooth Muscle Actin (ACTA2) AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
Clone
-
-
Épitope
- N-Term
-
Specificité
-
This antibody recognises ACTIN alpha Smooth Muscle.
Cellular Localization: Cytoplasmic. -
Attributs du produit
- Synonyms: Alpha-actin-2, ACTVS, GIG46, Cell growth-inhibiting gene 46 protein
-
Purification
- Purified
-
Immunogène
- N-terminal decapeptide of alpha smooth muscle isoform of actin, acetylated at theN-terminus. Remarks: Epitope: Acetyl group with N- terminal four amino acids of peptide chain of alphasmooth muscle.
-
Isotype
- IgG2a
-
-
-
-
Indications d'application
-
Suitable for Immunohistochemistry and Immunocytochemistry (Frozen or Formalin-FixedParaffin-Embedded (FFPE) tissue sections and cell smears)For IHC dilute concentared antibody at 1/50-1/100, use streptavidinapprox. biotin system orpolymer system, incubate 30 minutes at room temperature. Recommended Positive Control: Human uterus, gastrointestinal tissue, Leiomyosarcoma.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
Restrictions
- For Research Use only
-
-
-
Format
- Liquid
-
Concentration
- 0.2 mg/mL
-
Buffer
- PBS, pH 7.4 containing 1 % BSA as stabilizer and 0.05 % Sodium Azide as preservative.
-
Agent conservateur
- Sodium azide
-
Précaution d'utilisation
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
Stock
- -20 °C
-
Stockage commentaire
-
Storethe antibody undiluted at 2-8 °Cfor one month or (in aliquots) at -28 °Cfor longer. Avoid repeated freezing and thawing.
Shelf life: One year from despatch. -
Date de péremption
- 12 months
-
-
- Smooth Muscle Actin (ACTA2) (Actin, alpha 2, Smooth Muscle, Aorta (ACTA2))
-
Sujet
- Actin is a globular, roughly 42- kDa protein found in all eukaryotic cells. Actin participates in many important cellular functions, including muscle contraction cell motility cell division and cytokinesis vesicle and organelle movement, cell signaling, and the establishment and maintenance of cell junctions and cell shape. Expression of smooth muscle alpha actin is regulated by hormones and cell proliferation and is altered by pathological conditions including onogenic transformation and atherosclerosis.Synonyms: ACTSA, ACTVS, Alpha-actin-2, Cell growth-inhibiting gene 46 protein
-
ID gène
- 59
-
UniProt
- P62736
-
Pathways
- Myometrial Relaxation and Contraction, Skeletal Muscle Fiber Development
Antigène
-