Botulinum Neurotoxin Type B (BoNT/B) anticorps
Cet anticorps Souris Monoclonal détecte spécifiquement Botulinum Neurotoxin Type B dans cELISA et FACS. Il présente une réactivité avec des échantillons de Clostridium botulinum.
N° du produit ABIN179725
396,92 €
Plus frais de livraison 40,00 € et TVA
100 μg
Destination:
France
Envoi sous 3 à 4 jours ouvrables
Aperçu rapide pour Botulinum Neurotoxin Type B (BoNT/B) anticorps (ABIN179725)
Antigène
Voir toutes Botulinum Neurotoxin Type B (BoNT/B) Anticorps
Botulinum Neurotoxin Type B (BoNT/B)
Reactivité
Clostridium botulinum
Hôte
Souris
Clonalité
Monoclonal
Conjugué
Inconjugué
Application
Cell-ELISA (cELISA), Flow Cytometry (FACS)
Clone
GR-3G7
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Specificité
- Anti-BoNT/B
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Purification
- Protein G
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Immunogène
- genetic immunisation with cDNA encoding BoNT/B
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Isotype
- IgG1
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anti-Botulinum Neurotoxin Type B (BoNT/B) antibody
BoNT/B Reactivité: Clostridium botulinum ELISA, WB Hôte: Chicken egg unconjugated
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Indications d'application
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Flow cytometry: 1.2 µg/10^6 cells
CELISA: 1:200 - 1:400
For each application a titration should be performed to determine the optimal concentration. -
Restrictions
- For Research Use only
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Concentration
- 2 mg/mL
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Buffer
- PBS, pH 7.2
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Conseil sur la manipulation
- Avoid repeated freezing and thawing.
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Stock
- 4 °C
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Stockage commentaire
- short term: 2 °C - 8 °C, long term: -20 °C
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- Botulinum Neurotoxin Type B (BoNT/B)
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Autre désignation
- BoNT B, Lightchain
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Classe de substances
- Bacteria
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Sujet
- Botulinum neurotoxin type B (BoNT/B) is produced by Clostridium botulinum, a genetically diverse class of anaerobic, spore-forming, gram-positive bacilli. Seven different botulinum toxin groups have been identified serologically and are called botulinum toxin type A,B,C,D,E,F, and G. BoNT/B is a two-chain polypeptide with a 100-kDa heavy chain, which is responsible for neurospecific binding joined by a disulphide bond to a 50-kDa light chain, a zinc-endopeptidase which blocks neurotransmitter release. BoNT/B is one of the most poisonous naturally occurring substances. It inhibits acetylcholine release from neuromuscular junctions while it is used as an important therapeutic mainstay in the treatment of spasticity disorders and as a cosmetic treatment.
Antigène
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