P110 (Mitochondrial Membrane Protein) anticorps
Cet anticorps anti-P110 (Mitochondrial Membrane Protein) Monoclonal Souris (Clone 2G2) (ABIN306552) détecte spécifiquement P110 (Mitochondrial Membrane Protein) dans IF et WB.
L’anticorps est réactif avec des échantillons de Humain et Singe.
N° du produit ABIN306552
461,03 €
Plus frais de livraison 40,00 € et TVA
100 μg
Destination:
France
Envoi sous 8 à 12 jours ouvrables
Aperçu rapide pour P110 (Mitochondrial Membrane Protein) anticorps (ABIN306552)
Antigène
P110 (Mitochondrial Membrane Protein)
Reactivité
Humain, Singe
Hôte
Souris
Clonalité
Monoclonal
Conjugué
Inconjugué
Application
Immunofluorescence (IF), Western Blotting (WB)
Clone
2G2
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Fonction
- Mouse anti Human P110 (mitochondrial membrane protein)
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Réactivité croisée
- Humain
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Attributs du produit
- P110 is a human mitochondrial protein with a molecular weight of 110 kDa. Close examination of the staining pattern in HeLa and Fanconi's Anemia cells reveal differences in the morphology and organization of mitochondria in these two cell types. The epitope targeted may serve as a valuable marker in the investigation of relationships between mitochondria and other cellular structures in human cells. The mouse monoclonal P110 antibody labels mitochondria in human cells, as assessed by double staining with either Rhodamine 123 or a polyclonal antibody to mitochondrial matrix HSP-60 proteins. The P110 antigen has an approximate isoelectric point of 6.5 that copartitions with HSP-60 proteins during isolation of mitochondria from HeLa cells. The P110 staining pattern in HeLa and Fanconi's anaemia cells reveals differences in the morphology and organization of mitochondria in these two cell types. In HeLa cells, mitochondria appear as individual tubular compartments of variable length and are closely associated with vimentin filaments, particularly at the periphery of the nucleus. In Fanconi's anaemia cells, mitochondria have a filamentous shape and form an interconnected cytoplasmic reticulum running in parallel with both vimentin filaments and microtubules. After stabilization with aldehyde- or alcohol-based fixation protocols that optimize the preservation of cytoskeletal components, the epitope targeted by the 2G2 antibody may serve as a valuable marker in the investigation of relationships between mitochondria and other cellular structures in human cells.
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Purification
- Protein A/G Chromatography
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Immunogène
- Skeletal fracrtion of HeLa-S3 cells
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Isotype
- IgG1
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Indications d'application
- Application: Western Blot at 2-10 μg/mL. Immunofluorescence staining.
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Restrictions
- For Research Use only
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Format
- Liquid
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Buffer
- phosphate buffered saline with 0.08 % sodium azide
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- -20 °C
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Stockage commentaire
- Product should be stored at -20°C. Aliquot to avoid freeze/thaw cycles
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- P110 (Mitochondrial Membrane Protein)
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Sujet
- 2G2, mitochondrial membrane protein, p110
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UniProt
- Q9KGY0
Antigène
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