Osteoprotegerin anticorps (AA 20-37)
Aperçu rapide pour Osteoprotegerin anticorps (AA 20-37) (ABIN296455)
Antigène
Voir toutes Osteoprotegerin (TNFRSF11B) AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
Clone
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Épitope
- AA 20-37
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Specificité
- The Osteoprotegerin antibody, clone 98A1071, detects all forms of Osteoprotegerin including monomeric, dimeric and Osteoprotegerin bound to RANKL (Vandooren, 2008) as well as Osteoprotegerin bound to TRAIL (Sandra, 2006).
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Homologie
- Percent identity by BLAST analysis: Human, Gibbon (100%) Monkey (94%) Marmoset, Panda, Dog, Horse, Pig, Opossum (89%) Mouse, Rat, Elephant, Bovine (83%).
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Purification
- Protein G purified
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Immunogène
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A peptide corresponding to the amino acids 20-37 TQETFPPKYLHYDEETSH of human OPG. The specificity was tested on recombinant OPG by western blot analysis. Percent identity by BLAST analysis: Human, Gibbon (100%), Monkey (94%), Marmoset, Panda, Dog, Horse, Pig, Opossum (89%), Mouse, Rat, Elephant, Bovine (83%).
Type of Immunogen: Recombinant protein -
Isotype
- IgG
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Indications d'application
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Approved: IHC, IHC-P (5 μg/mL), WB
Usage: Immunohistochemistry: This antibody was validated for use in immunohistochemistry on a panel of 21 formalin-fixed, paraffin-embedded (FFPE) human tissues after heat induced antigen retrieval in pH 6.0 citrate buffer. After incubation with the primary antibody, slides were incubated with biotinylated secondary antibody, followed by alkaline phosphatase-streptavidin and chromogen. The stained slides were evaluated by a pathologist to confirm staining specificity. The optimal working concentration for this antibody was determined to be 5 μg/mL. -
Commentaires
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Target Species of Antibody: Human
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- Lot specific
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Buffer
- PBS, 0.05 % BSA, 0.05 % sodium azide. Sourced in TCS.
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Conseil sur la manipulation
- Avoid repeat freeze-thaw cycles.
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Stock
- 4 °C,-20 °C
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Stockage commentaire
- Short term: 4°C. Long term: Store at -20°C. Avoid freeze-thaw cycles.
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- Osteoprotegerin (TNFRSF11B) (Tumor Necrosis Factor Receptor Superfamily, Member 11b (TNFRSF11B))
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Autre désignation
- Osteoprotegerin / OPG
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Classe de substances
- Chemical
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Sujet
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Name/Gene ID: TNFRSF11B
Family: TNF Receptor
Synonyms: TNFRSF11B, OCIF, OPG, Osteoprotegerin, TR1 -
ID gène
- 4982
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UniProt
- O00300
Antigène
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