gamma 1 Adaptin anticorps (AA 642-821)
(5 références)Aperçu rapide pour gamma 1 Adaptin anticorps (AA 642-821) (ABIN967934)
Antigène
Voir toutes gamma 1 Adaptin (AP1G1) AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
Clone
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Épitope
- AA 642-821
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Réactivité croisée
- Rat (Rattus), Humain, Chien
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Attributs du produit
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1. Since applications vary, each investigator should titrate the reagent to obtain optimal results.
2. Please refer to us for technical protocols.
3. Caution: Sodium azide yields highly toxic hydrazoic acid under acidic conditions. Dilute azide compounds in running water before discarding to avoid accumulation of potentially explosive deposits in plumbing.
4. Source of all serum proteins is from USDA inspected abattoirs located in the United States. -
Purification
- The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography.
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Immunogène
- Mouse Adaptin gamma aa. 642-821
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Isotype
- IgG1
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anti-Adaptor-Related Protein Complex 1, gamma 1 Subunit (AP1G1) (AA 721-822) antibody
AP1G1 Reactivité: Humain, Souris, Rat WB, ELISA, IF (cc), IF (p), IHC (p), IHC (fro), ICC Hôte: Lapin Polyclonal unconjugated
anti-Adaptor-Related Protein Complex 1, gamma 1 Subunit (AP1G1) (AA 592-686) antibodyAP1G1 Reactivité: Humain ELISA, IHC, IF Hôte: Lapin Polyclonal unconjugated
anti-Adaptor-Related Protein Complex 1, gamma 1 Subunit (AP1G1) antibodyAP1G1 Reactivité: Humain WB, IHC Hôte: Lapin Monoclonal unconjugated
anti-Adaptor-Related Protein Complex 1, gamma 1 Subunit (AP1G1) antibodyKD Validated AP1G1 Reactivité: Humain WB, FACS Hôte: Lapin Monoclonal 23GB3655 unconjugated Recombinant Antibody
anti-Adaptor-Related Protein Complex 1, gamma 1 Subunit (AP1G1) (C-Term) antibodyAP1G1 Reactivité: Humain, Souris, Rat, Boeuf (Vache), Chien, Cheval, Porc, Lapin WB Hôte: Lapin Polyclonal unconjugated
anti-Adaptor-Related Protein Complex 1, gamma 1 Subunit (AP1G1) (AA 574-623) antibodyAP1G1 Reactivité: Humain, Souris, Rat, Boeuf (Vache), Chien, Cheval, Porc, Lapin, Singe, Roussette (Chauve-souris), Hamster WB, IHC, IHC (p) Hôte: Lapin Polyclonal unconjugated
anti-Adaptor-Related Protein Complex 1, gamma 1 Subunit (AP1G1) (AA 1-50) antibodyAP1G1 Reactivité: Humain, Souris WB, IP Hôte: Lapin Polyclonal unconjugated
anti-Adaptor-Related Protein Complex 1, gamma 1 Subunit (AP1G1) antibodyKD Validated AP1G1 Reactivité: Humain, Souris, Rat WB, IHC Hôte: Lapin Monoclonal unconjugated Recombinant Antibody
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Commentaires
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Related Products: ABIN968539, ABIN967389
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 250 μg/mL
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Buffer
- Aqueous buffered solution containing BSA, glycerol, and ≤0.09 % sodium azide.
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- -20 °C
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Stockage commentaire
- Store undiluted at -20°C.
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: "SVIP is a novel VCP/p97-interacting protein whose expression causes cell vacuolation." dans: Molecular biology of the cell, Vol. 14, Issue 1, pp. 262-73, (2003) (PubMed).
: "Role of LAMP-2 in lysosome biogenesis and autophagy." dans: Molecular biology of the cell, Vol. 13, Issue 9, pp. 3355-68, (2002) (PubMed).
: "Clint: a novel clathrin-binding ENTH-domain protein at the Golgi." dans: Molecular biology of the cell, Vol. 13, Issue 11, pp. 4060-73, (2002) (PubMed).
: "Enthoprotin: a novel clathrin-associated protein identified through subcellular proteomics." dans: The Journal of cell biology, Vol. 158, Issue 5, pp. 855-62, (2002) (PubMed).
: "Cloning and expression of gamma-adaptin, a component of clathrin-coated vesicles associated with the Golgi apparatus." dans: The Journal of cell biology, Vol. 111, Issue 6 Pt 1, pp. 2319-26, (1991) (PubMed).
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- gamma 1 Adaptin (AP1G1) (Adaptor-Related Protein Complex 1, gamma 1 Subunit (AP1G1))
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Autre désignation
- Adaptin gamma
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Sujet
- Sorting of integral membrane proteins at various stages of the endocytic and secretory pathways is mediated by vesicular trafficking between a variety of organelles. Two sorting signals are tyrosine-based and dileucine-based signals that interact with heterotetrameric adaptor protein complexes (AP-1, AP-2, AP-3, and AP-4), which are associated with the vesicle coats. These coatomers contain two large Adaptin proteins (gamma, alpha, delta, or epsilon and beta1, beta2, beta3, or beta4, respectively) that are noncovalently linked to one medium chain (µ1, µ2, µ3, or µ4) and one small chain ( sigma1, sigma2, sigma3, or sigma4). The AP-1 and AP-3 complexes are involved in protein sorting from the TGN and endosomes, while AP-2 adaptor complexes are involved in clathrin-mediated endocytosis. Adaptin gamma shows more homology with Adaptin alpha than with Adaptin beta. The conserved regions between Adaptins gamma and alpha could be important for binding to other components of the AP-1 and AP-2 complexes, respectively.
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Poids moléculaire
- 104 kDa
Antigène
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