NMDAR2A anticorps (AA 1093-1214)
(2 références)Aperçu rapide pour NMDAR2A anticorps (AA 1093-1214) (ABIN968802)
Antigène
Voir toutes NMDAR2A (GRIN2A) AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
Clone
-
-
Épitope
- AA 1093-1214
-
Réactivité croisée
- Rat (Rattus)
-
Attributs du produit
-
1. Since applications vary, each investigator should titrate the reagent to obtain optimal results.
2. Please refer to us for technical protocols.
3. Caution: Sodium azide yields highly toxic hydrazoic acid under acidic conditions. Dilute azide compounds in running water before discarding to avoid accumulation of potentially explosive deposits in plumbing.
4. Source of all serum proteins is from USDA inspected abattoirs located in the United States. -
Purification
- The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography.
-
Immunogène
- Mouse NMDAR2A aa. 1093-1214
-
Isotype
- IgG1
-
-
anti-Glutamate Receptor, Ionotropic, N-Methyl D-Aspartate 2a (GRIN2A) (AA 851-950) antibody
GRIN2A Reactivité: Rat, Souris WB, ELISA Hôte: Lapin Polyclonal unconjugated
anti-Glutamate Receptor, Ionotropic, N-Methyl D-Aspartate 2a (GRIN2A) (AA 41-53), (Extracellular) antibodyGRIN2A Reactivité: Rat WB, IHC, IF, IP, FACS, IC, LCI Hôte: Lapin Polyclonal unconjugated
anti-Glutamate Receptor, Ionotropic, N-Methyl D-Aspartate 2a (GRIN2A) (AA 501-750) antibodyGRIN2A Reactivité: Humain WB, IHC, ELISA, IF Hôte: Lapin Polyclonal unconjugated
anti-Glutamate Receptor, Ionotropic, N-Methyl D-Aspartate 2a (GRIN2A) (AA 23-165) antibodyGRIN2A Reactivité: Humain ELISA, FACS Hôte: Souris Monoclonal 3G10F9 unconjugated
anti-Glutamate Receptor, Ionotropic, N-Methyl D-Aspartate 2a (GRIN2A) (AA 75-325) antibody (APC)GRIN2A Reactivité: Rat WB, IHC, ICC, IF Hôte: Souris Monoclonal S327-95 APC
anti-Glutamate Receptor, Ionotropic, N-Methyl D-Aspartate 2a (GRIN2A) (AA 75-325) antibody (HRP)GRIN2A Reactivité: Rat WB, IHC, ICC, IF Hôte: Souris Monoclonal S327-95 HRP
anti-Glutamate Receptor, Ionotropic, N-Methyl D-Aspartate 2a (GRIN2A) (AA 75-325) antibody (Atto 488)GRIN2A Reactivité: Rat WB, IHC, ICC, IF Hôte: Souris Monoclonal S327-95 Atto 488
anti-Glutamate Receptor, Ionotropic, N-Methyl D-Aspartate 2a (GRIN2A) (AA 75-325) antibody (Atto 390)GRIN2A Reactivité: Rat WB, IHC, ICC, IF Hôte: Souris Monoclonal S327-95 Atto 390
anti-Glutamate Receptor, Ionotropic, N-Methyl D-Aspartate 2a (GRIN2A) (AA 75-325) antibody (Atto 594)GRIN2A Reactivité: Rat WB, IHC, ICC, IF Hôte: Souris Monoclonal S327-95 Atto 594
anti-Glutamate Receptor, Ionotropic, N-Methyl D-Aspartate 2a (GRIN2A) (AA 75-325) antibody (Biotin)GRIN2A Reactivité: Rat WB, IHC, ICC, IF Hôte: Souris Monoclonal S327-95 Biotin
-
-
Commentaires
-
Related Products: ABIN968540, ABIN967389
-
Restrictions
- For Research Use only
-
-
-
Format
- Liquid
-
Concentration
- 250 μg/mL
-
Buffer
- Aqueous buffered solution containing BSA, glycerol, and ≤0.09 % sodium azide.
-
Agent conservateur
- Sodium azide
-
Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
Stock
- -20 °C
-
Stockage commentaire
- Store undiluted at -20° C.
-
-
-
: "Attenuation of focal ischemic brain injury in mice deficient in the epsilon1 (NR2A) subunit of NMDA receptor." dans: The Journal of neuroscience : the official journal of the Society for Neuroscience, Vol. 18, Issue 23, pp. 9727-32, (1998) (PubMed).
: "Molecular characterization of the family of the N-methyl-D-aspartate receptor subunits." dans: The Journal of biological chemistry, Vol. 268, Issue 4, pp. 2836-43, (1993) (PubMed).
-
-
- NMDAR2A (GRIN2A) (Glutamate Receptor, Ionotropic, N-Methyl D-Aspartate 2a (GRIN2A))
-
Autre désignation
- NMDAR2A
-
Sujet
-
The majority of synapses in the central nervous system utilize glutamate as a neurotransmitter to produce rapid neuronal excitation. Glutamate has a diverse array of receptors that can be categorized into two groups, ionotropic and metabotropic. The ionotropic receptors are subdivided into two distinct types: 1) receptors for N-methyl D-aspartate (NMDAR) and 2) non-NMDA receptors for AMPA and kainate. Four types of NMDAR2 have been identified: NMDAR2A (NR2A), NR2B, NR2C, and NR2D. NR2A and NR2B contain a C-terminal extension (> 600 amino acids) that has small, scattered regions of conserved sequence. In embryonic stages, NR2B is expressed throughout the brain, while NR2D is found in diencephalon and brainstem. After birth, NR2A is found throughout the brain, and NR2C is expressed in cerebellum. At this time, NR2B expression becomes restricted to the forebrain, and NR2D expression is strongly reduced. Deletion of the most widespread postnatal NR subunit, NR2A, does not have adverse affects on brain development, but reduces long-term potentiation (LTP) in the hippocampus and impairs spatial and contextual learning. Thus, NR2A may be critical for postnatal learning. This antibody is routinely tested by western blot analysis.
Synonyms: N-Methyl D-Aspartate -
Poids moléculaire
- 180 kDa
-
Pathways
- Synaptic Membrane, Regulation of long-term Neuronal Synaptic Plasticity
Antigène
-
