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SLC3A2 anticorps (AA 9-204)

Name: SLC3A2 anticorps (AA 9-204)
SKU: ABIN968570
Availability: InStock

Il existe 4+ publications pour ce produit. L’anticorps anti-SLC3A2 Monoclonal Souris est utilisé pour la détection de SLC3A2 dans des échantillons de Chemical. Il a été validé pour WB et IF.

Western blot analysis of CD98HC on rat liver lysate. (SLC3A2 anticorps (AA 9-204))

Chick Fibroblast (SLC3A2 anticorps (AA 9-204))

Image no. 3 for anti-Solute Carrier Family 3 (Activators of Dibasic and Neutral Amino Acid Transport), Member 2 (SLC3A2) (AA 9-204) antibody (ABIN968570) (SLC3A2 anticorps (AA 9-204))

Western Blotting (WB) image for anti-Solute Carrier Family 3 (Activators of Dibasic and Neutral Amino Acid Transport), Member 2 (SLC3A2) (AA 9-204) antibody (ABIN968570) (SLC3A2 anticorps (AA 9-204))

4 images

(4 références)

N° du produit ABIN968570

164,17 €

Plus frais de livraison 40,00 € et TVA

50 μg

Destination: France

Envoi sous 12 à 15 jours ouvrables

Aperçu rapide pour SLC3A2 anticorps (AA 9-204) (ABIN968570)

Antigène

Voir toutes SLC3A2 Anticorps

SLC3A2 (Solute Carrier Family 3 (Activators of Dibasic and Neutral Amino Acid Transport), Member 2 (SLC3A2))

Reactivité

Chemical

Hôte

Souris

Clonalité

Monoclonal

Conjugué

Cet anticorp SLC3A2 est non-conjugé

Application

Western Blotting (WB), Immunofluorescence (IF)

Clone

30-CD98HC

Discover our top product SLC3A2 Anticorps primaire

Épitope
15

9

5

4

3

3

2

2

1

1

1

1

1

1

1

1

1

1

1

1

1

1
AA 9-204

Attributs du produit

1. Since applications vary, each investigator should titrate the reagent to obtain optimal results.
2. Please refer to us for technical protocols.
3. Caution: Sodium azide yields highly toxic hydrazoic acid under acidic conditions. Dilute azide compounds in running water before discarding to avoid accumulation of potentially explosive deposits in plumbing.
4. Source of all serum proteins is from USDA inspected abattoirs located in the United States.

Purification

The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography.

Immunogène

Rat 4F2 hc aa. 9-204

Isotype

IgG1
anti-Solute Carrier Family 3 (Activators of Dibasic and Neutral Amino Acid Transport), Member 2 (SLC3A2) (AA 1-529) antibody
SLC3A2 Reactivité: Humain WB Hôte: Lapin Polyclonal unconjugated

anti-Solute Carrier Family 3 (Activators of Dibasic and Neutral Amino Acid Transport), Member 2 (SLC3A2) (AA 360-529) antibody
SLC3A2 Reactivité: Humain WB, IHC, IF Hôte: Lapin Polyclonal unconjugated

anti-Solute Carrier Family 3 (Activators of Dibasic and Neutral Amino Acid Transport), Member 2 (SLC3A2) (AA 150-164), (Extracellular) antibody
SLC3A2 Reactivité: Souris WB, FACS, IHC, LCI Hôte: Lapin Polyclonal unconjugated

anti-Solute Carrier Family 3 (Activators of Dibasic and Neutral Amino Acid Transport), Member 2 (SLC3A2) (AA 213-349) antibody
SLC3A2 Reactivité: Humain WB, IHC, IP, ICC Hôte: Lapin Polyclonal unconjugated

anti-Solute Carrier Family 3 (Activators of Dibasic and Neutral Amino Acid Transport), Member 2 (SLC3A2) (AA 231-280) antibody
SLC3A2 Reactivité: Humain, Rat, Porc WB, ELISA, IHC (p), IF (p), IF (cc), IHC (fro) Hôte: Lapin Polyclonal unconjugated

anti-Solute Carrier Family 3 (Activators of Dibasic and Neutral Amino Acid Transport), Member 2 (SLC3A2) (AA 588-615), (C-Term) antibody
SLC3A2 Reactivité: Humain WB, IHC (p) Hôte: Lapin Polyclonal RB22529 unconjugated

anti-Solute Carrier Family 3 (Activators of Dibasic and Neutral Amino Acid Transport), Member 2 (SLC3A2) antibody (FITC)
SLC3A2 Reactivité: Humain FACS Hôte: Souris Monoclonal MEM-108 FITC

anti-Solute Carrier Family 3 (Activators of Dibasic and Neutral Amino Acid Transport), Member 2 (SLC3A2) antibody (Biotin)
SLC3A2 Reactivité: Humain FACS, IP, IHC (p) Hôte: Souris Monoclonal MEM-108 Biotin

anti-Solute Carrier Family 3 (Activators of Dibasic and Neutral Amino Acid Transport), Member 2 (SLC3A2) antibody
SLC3A2 Reactivité: Souris FACS, IP, St Hôte: Lapin Chimeric RL388 unconjugated Recombinant Antibody

anti-Solute Carrier Family 3 (Activators of Dibasic and Neutral Amino Acid Transport), Member 2 (SLC3A2) (AA 285-521) antibody
SLC3A2 Reactivité: Souris WB, IHC, IP, ICC Hôte: Lapin Polyclonal unconjugated

Commentaires

Related Products: ABIN967389, ABIN968548

Restrictions

For Research Use only
Format

Liquid

Concentration

250 μg/mL

Buffer

Aqueous buffered solution containing BSA, glycerol, and ≤0.09 % sodium azide.

Agent conservateur

Sodium azide

Précaution d'utilisation

This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock

-20 °C

Stockage commentaire

Store undiluted at -20°C.
Nakamura, Sato, Yang, Miyagawa, Harasaki, Tomita, Matsuoka, Noma, Iwai, Minato: "4F2 (CD98) heavy chain is associated covalently with an amino acid transporter and controls intracellular trafficking and membrane topology of 4F2 heterodimer." dans: The Journal of biological chemistry, Vol. 274, Issue 5, pp. 3009-16, (1999) (PubMed).

Tsurudome, Ito, Takebayashi, Okumura, Nishio, Kawano, Kusagawa, Komada, Ito: "Cutting edge: primary structure of the light chain of fusion regulatory protein-1/CD98/4F2 predicts a protein with multiple transmembrane domains that is almost identical to the amino acid transporter E16." dans: Journal of immunology (Baltimore, Md. : 1950), Vol. 162, Issue 5, pp. 2462-6, (1999) (PubMed).

Kanai, Segawa, Miyamoto, Uchino, Takeda, Endou: "Expression cloning and characterization of a transporter for large neutral amino acids activated by the heavy chain of 4F2 antigen (CD98)." dans: The Journal of biological chemistry, Vol. 273, Issue 37, pp. 23629-32, (1998) (PubMed).

Fenczik, Sethi, Ramos, Hughes, Ginsberg: "Complementation of dominant suppression implicates CD98 in integrin activation." dans: Nature, Vol. 390, Issue 6655, pp. 81-5, (1997) (PubMed).
Antigène

SLC3A2 (Solute Carrier Family 3 (Activators of Dibasic and Neutral Amino Acid Transport), Member 2 (SLC3A2))

Autre désignation

CD98HC

Classe de substances

Chemical

Sujet

4F2 antigen (CD98) was identified as a heterodimer consisting of an 80 kDa type II glycosylated integral membrane protein 4F2 heavy chain (4F2 hc) linked by disulfide bonds to a hydrophobic, non-glycosylated, 37 kDa protein 4F2 light chain (4F2 lc). The 4F2 hc colocalizes with cadherins at cell adhesion sites and is required for the intracellular targeting of 4F2 heterodimers. 4F2 hc also associates with beta1 integrins and overexpression of 4F2 reverses the suppression of beta1 integrin activation caused by overexpression of beta1 cytoplasmic domains. 4F2 has also been identified as a fusion regulatory protein FRP-1, since anti-FRP-1 antibodies can induce HIV-mediated cell fusion via an integrin system. 4F2 heterodimers are also important for activation of amino acid transport. 4F2 hc is 30% homologous with the amino acid transport activator D2/rBAT and expression of 4F2 hc in Xenopus oocytes induces system y+L amino acid transport. Thus, 4F2 hc may participate in intracellular trafficking and activation of amino acid transporters, as well as in the regulation of integrin signaling.
Synonyms: 4F2 hc

Poids moléculaire

80 kDa