RUNX1T1 anticorps (Middle Region)
Aperçu rapide pour RUNX1T1 anticorps (Middle Region) (ABIN504421)
Antigène
Voir toutes RUNX1T1 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- Middle Region
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Séquence
- RQCNLQQFIQ QTGAALPPPP RPDRGPPGTQ GPLPPAREES LLGAPSESHA
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Homologie
- Cow: 100%, Dog: 100%, Guinea Pig: 93%, Horse: 93%, Human: 100%, Mouse: 93%, Pig: 100%, Rabbit: 100%, Rat: 86%, Zebrafish: 93%
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Attributs du produit
- This is a rabbit polyclonal antibody against RUNX1T1. It was validated on Western Blot using a cell lysate as a positive control.
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Purification
- Affinity Purified
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Immunogène
- The immunogen is a synthetic peptide directed towards the middle region of human RUNX1T1
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anti-Runt-Related Transcription Factor 1, Translocated To, 1 (Cyclin D-Related) (RUNX1T1) (Internal Region), (N-Term) antibody
RUNX1T1 Reactivité: Humain ELISA, ChIP Hôte: Lapin Polyclonal unconjugated
anti-Runt-Related Transcription Factor 1, Translocated To, 1 (Cyclin D-Related) (RUNX1T1) (AA 416-525) antibodyRUNX1T1 Reactivité: Humain WB, ELISA, IF Hôte: Souris Monoclonal 5A12 unconjugated
anti-Runt-Related Transcription Factor 1, Translocated To, 1 (Cyclin D-Related) (RUNX1T1) (Internal Region) antibodyRUNX1T1 Reactivité: Humain WB, IP Hôte: Lapin Polyclonal unconjugated
anti-Runt-Related Transcription Factor 1, Translocated To, 1 (Cyclin D-Related) (RUNX1T1) (AA 416-525) antibodyRUNX1T1 Reactivité: Humain WB, ELISA, IHC Hôte: Lapin Polyclonal unconjugated
anti-Runt-Related Transcription Factor 1, Translocated To, 1 (Cyclin D-Related) (RUNX1T1) (AA 1-577) antibodyRUNX1T1 Reactivité: Humain WB, PLA Hôte: Lapin Polyclonal unconjugated
anti-Runt-Related Transcription Factor 1, Translocated To, 1 (Cyclin D-Related) (RUNX1T1) (AA 335-510) antibodyRUNX1T1 Reactivité: Humain, Souris, Rat WB, ELISA, IHC, IF, IP, FACS, ICC Hôte: Lapin Polyclonal unconjugated
anti-Runt-Related Transcription Factor 1, Translocated To, 1 (Cyclin D-Related) (RUNX1T1) (AA 100-390) antibodyRUNX1T1 Reactivité: Humain WB Hôte: Lapin Polyclonal unconjugated
anti-Runt-Related Transcription Factor 1, Translocated To, 1 (Cyclin D-Related) (RUNX1T1) (N-Term) antibodyRUNX1T1 Reactivité: Humain, Souris, Rat, Chien, Poisson zèbre (Danio rerio), Lapin, Cobaye, Cheval, Boeuf (Vache), Porc, Poulet, Singe, Roussette (Chauve-souris) WB Hôte: Lapin Polyclonal unconjugated
anti-Runt-Related Transcription Factor 1, Translocated To, 1 (Cyclin D-Related) (RUNX1T1) (AA 288-337) antibodyRUNX1T1 Reactivité: Humain, Rat, Chien, Lapin, Porc, Singe WB Hôte: Lapin Polyclonal unconjugated
anti-Runt-Related Transcription Factor 1, Translocated To, 1 (Cyclin D-Related) (RUNX1T1) (AA 221-270) antibodyRUNX1T1 Reactivité: Humain, Souris, Rat, Chien, Poisson zèbre (Danio rerio), Lapin, Cobaye, Cheval, Porc, Poulet, Singe, Roussette (Chauve-souris) WB Hôte: Lapin Polyclonal unconjugated
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Indications d'application
- Optimal working dilutions should be determined experimentally by the investigator.
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Commentaires
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Antigen size: 577 AA
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- Lot specific
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Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Conseil sur la manipulation
- Avoid repeated freeze-thaw cycles.
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Stock
- -20 °C
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Stockage commentaire
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- RUNX1T1 (Runt-Related Transcription Factor 1, Translocated To, 1 (Cyclin D-Related) (RUNX1T1))
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Autre désignation
- RUNX1T1
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Sujet
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RUNX1T1 is a putative zinc finger transcription factor and oncoprotein. In acute myeloid leukemia, especially in the M2 subtype, the t(8,21)(q22,q22) translocation is one of the most frequent karyotypic abnormalities. The translocation produces a chimeric gene made up of the 5'-region of the RUNX1 gene fused to the 3'-region of this gene. The chimeric protein is thought to associate with the nuclear corepressor/histone deacetylase complex to block hematopoietic differentiation. The protein encoded by this gene is a putative zinc finger transcription factor and oncoprotein. In acute myeloid leukemia, especially in the M2 subtype, the t(8,21)(q22,q22) translocation is one of the most frequent karyotypic abnormalities. The translocation produces a chimeric gene made up of the 5'-region of the RUNX1 gene fused to the 3'-region of this gene. The chimeric protein is thought to associate with the nuclear corepressor/histone deacetylase complex to block hematopoietic differentiation. Several transcript variants encoding multiple isoforms have been found for this gene.
Alias Symbols: AML1T1, CBFA2T1, CDR, ETO, MGC2796, MTG8, MTG8b, ZMYND2
Protein Interaction Partner: EPS8, NECAB2, ABI3, GSE1, MID2, SPRY2, HOMER3, LPXN, ZMYM4, STX11, MEOX2, CCDC36, TRIM42, SPERT, CREB3L1, LZTS2, EFHC2, CPSF7, C19orf57, PRDM14, CBFA2T2, NCOR1, UBQLN4, ATN1, BCL6, ETS1, RUNX1, DNMT1, SPEN, RBPJ, UBE2E2, UBC, TRIM33, HDAC1, NCOR2, SIN3A,
Protein Size: 577 -
Poids moléculaire
- 64 kDa
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ID gène
- 862
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NCBI Accession
- NM_004349, NP_004340
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UniProt
- B2R6I9
Antigène
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