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MYB anticorps (Internal Region)

L’anticorps anti-MYB Polyclonal Lapin est utilisé pour la détection de MYB dans des échantillons de Humain, Souris, Rat, Cheval, Porc, Singe, Bonobo, Chimpanzé, Gorilla, Opossum et Orang-Utan. Il a été validé pour WB et EIA.
N° du produit ABIN401456
579,99 €
Plus frais de livraison 40,00 € et TVA
Destination: France
Envoi sous 17 jours ouvrables

Aperçu rapide pour MYB anticorps (Internal Region) (ABIN401456)

Antigène

Voir toutes MYB Anticorps
MYB (V-Myb Myeloblastosis Viral Oncogene Homolog (Avian) (MYB))

Reactivité

  • 126
  • 48
  • 8
  • 8
  • 7
  • 5
  • 5
  • 5
  • 5
  • 4
  • 3
  • 2
  • 2
  • 1
Humain, Souris, Rat, Cheval, Porc, Singe, Bonobo, Chimpanzé, Gorilla, Opossum, Orang-Utan

Hôte

  • 109
  • 22
  • 2
  • 2
Lapin

Clonalité

  • 98
  • 37
Polyclonal

Conjugué

  • 87
  • 6
  • 3
  • 3
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Cet anticorp MYB est non-conjugé

Application

  • 102
  • 54
  • 51
  • 24
  • 17
  • 15
  • 13
  • 13
  • 10
  • 8
  • 3
  • 3
  • 1
  • 1
  • 1
  • 1
Western Blotting (WB), Enzyme Immunoassay (EIA)
  • Épitope

    • 15
    • 12
    • 12
    • 10
    • 8
    • 5
    • 5
    • 4
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Internal Region

    Specificité

    This antibody reacts with endogenous c-Myb protein and also SUMOylated overexpressed c-Myb protein in transfected Cos7 cells.

    Purification

    Affinity chromatography

    Immunogène

    Peptide corresponding to an internal portion of the c-Myb protein

    Isotype

    IgG
  • Indications d'application

    ELISA: 1/10,000 - 1/25,000. Western Blot: 1/250 - 1/1000.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.

    Restrictions

    For Research Use only
  • Format

    Liquid

    Concentration

    1.0 mg/mL (by UV absorbance at 280 nm)

    Buffer

    0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2 containing 0.01 % (w/v) Sodium Azide

    Agent conservateur

    Sodium azide

    Précaution d'utilisation

    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Conseil sur la manipulation

    Avoid repeated freezing and thawing.

    Stock

    -20 °C
  • Antigène

    MYB (V-Myb Myeloblastosis Viral Oncogene Homolog (Avian) (MYB))

    Autre désignation

    MYB

    Sujet

    The transcription factor c-Myb plays an important role in the development of all hematopoietic lineages during definitive hematopoiesis. Its critical role in hematopoiesis has been first demonstrated in experiments with targeted disruption of the c-Myb gene where deletion of both alleles of the c-Myb gene was embryonally lethal due to severe anemia. c-Myb is a short-lived sequence specific DNA-binding protein that regulates transcription of several important genes involved directly in cellular processes such as proliferation, differentiation, and apoptosis. Posttranslational modifications such as phosphorylation, acetylation, ubiquitination, and conjugation of SUMO proteins are crucial for modulation of the transactivation activity of c-Myb.Synonyms: Proto-oncogene c-Myb, Transcriptional activator Myb, c-Myb

    ID gène

    17863

    NCBI Accession

    NP_001185843

    UniProt

    P06876

    Pathways

    Chromatin Binding, Positive Regulation of Immune Effector Process
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