CACNB2 anticorps (Middle Region)
Aperçu rapide pour CACNB2 anticorps (Middle Region) (ABIN501437)
Antigène
Voir toutes CACNB2 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- Middle Region
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Séquence
- HLADYLEAYW KATHPPSSSL PNPLLSRTLA TSSLPLSPTL ASNSQGSQGD
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Homologie
- Cow: 86%, Guinea Pig: 86%, Human: 100%, Mouse: 92%, Rabbit: 93%, Rat: 93%
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Attributs du produit
- This is a rabbit polyclonal antibody against CACNB2. It was validated on Western Blot using a cell lysate as a positive control.
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Purification
- Affinity Purified
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Immunogène
- The immunogen is a synthetic peptide directed towards the middle region of human CACNB2
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Indications d'application
- Optimal working dilutions should be determined experimentally by the investigator.
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Commentaires
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Antigen size: 605 AA
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- Lot specific
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Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Conseil sur la manipulation
- Avoid repeated freeze-thaw cycles.
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Stock
- -20 °C
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Stockage commentaire
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- CACNB2 (Calcium Channel, Voltage-Dependent, beta 2 Subunit (CACNB2))
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Autre désignation
- CACNB2
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Sujet
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CACNB2 contributes to the function of the calcium channel by increasing peak calcium current, shifting the voltage dependencies of activation and inactivation, modulating G protein inhibition and controlling the alpha-1 subunit membrane targeting. Defects in CACNB2 are the cause of Brugada syndrome type 4 (BRS4).
Alias Symbols: CACNLB2, FLJ23743, MYSB, CAVB2
Protein Interaction Partner: REM1, PRKACA,
Protein Size: 605 -
Poids moléculaire
- 68 kDa
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ID gène
- 783
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NCBI Accession
- NM_201590, NP_963884
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UniProt
- Q08289
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Pathways
- Skeletal Muscle Fiber Development
Antigène
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