CHRNB2 anticorps (Middle Region)
Aperçu rapide pour CHRNB2 anticorps (Middle Region) (ABIN183541)
Antigène
Voir toutes CHRNB2 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
-
-
Épitope
- Middle Region
-
Séquence
- KIEVKHFPFD QQNCTMKFRS WTYDRTEIDL VLKSEVASLD DFTPSGEWDI
-
Homologie
- Cow: 93%, Dog: 93%, Guinea Pig: 93%, Human: 100%, Mouse: 93%, Pig: 100%, Rat: 93%, Yeast: 77%
-
Attributs du produit
- This is a rabbit polyclonal antibody against CHRNB2. It was validated on Western Blot using a cell lysate as a positive control.
-
Purification
- Protein A purified
-
Immunogène
- The immunogen is a synthetic peptide directed towards the middle region of human CHRNB2
-
-
anti-Cholinergic Receptor, Nicotinic, beta 2 (Neuronal) (CHRNB2) (AA 26-233) antibody
CHRNB2 Reactivité: Humain ELISA, FACS Hôte: Souris Monoclonal 2D12A2 unconjugated
anti-Cholinergic Receptor, Nicotinic, beta 2 (Neuronal) (CHRNB2) (AA 86-244) antibodyCHRNB2 Reactivité: Humain WB, IHC, ICC, IP Hôte: Lapin Polyclonal unconjugated
anti-Cholinergic Receptor, Nicotinic, beta 2 (Neuronal) (CHRNB2) (AA 322-458) antibodyCHRNB2 Reactivité: Humain WB, ELISA, IHC, IF Hôte: Lapin Polyclonal unconjugated
anti-Cholinergic Receptor, Nicotinic, beta 2 (Neuronal) (CHRNB2) (Internal Region) antibodyVerified CHRNB2 Reactivité: Humain WB, ELISA, IHC Hôte: Chèvre Polyclonal unconjugated
anti-Cholinergic Receptor, Nicotinic, beta 2 (Neuronal) (CHRNB2) (AA 26-130) antibodyCHRNB2 Reactivité: Humain WB, ELISA Hôte: Souris Monoclonal 1C7 unconjugated
anti-Cholinergic Receptor, Nicotinic, beta 2 (Neuronal) (CHRNB2) (AA 21-70) antibodyCHRNB2 Reactivité: Humain, Rat, Souris, Chien, Boeuf (Vache), Porc, Cobaye, Poisson zèbre (Danio rerio), Roussette (Chauve-souris), Singe, Xenopus laevis, Cheval WB, IHC, IHC (p) Hôte: Lapin Polyclonal unconjugated
anti-Cholinergic Receptor, Nicotinic, beta 2 (Neuronal) (CHRNB2) (AA 155-204) antibodyCHRNB2 Reactivité: Humain, Poulet WB, IHC, IHC (p) Hôte: Lapin Polyclonal unconjugated
anti-Cholinergic Receptor, Nicotinic, beta 2 (Neuronal) (CHRNB2) (AA 96-107), (Extracellular) antibody (Atto 594)CHRNB2 Reactivité: Rat IHC, IF, IC, LCI Hôte: Lapin Polyclonal Atto 594
anti-Cholinergic Receptor, Nicotinic, beta 2 (Neuronal) (CHRNB2) (AA 66-100) antibodyCHRNB2 Reactivité: Humain, Rat, Souris WB Hôte: Lapin Polyclonal RB53583 unconjugated
anti-Cholinergic Receptor, Nicotinic, beta 2 (Neuronal) (CHRNB2) antibodyCHRNB2 Reactivité: Humain, Rat, Souris ELISA, IHC Hôte: Lapin Polyclonal unconjugated
-
-
Indications d'application
- Optimal working dilutions should be determined experimentally by the investigator.
-
Commentaires
-
Antigen size: 502 AA
-
Restrictions
- For Research Use only
-
-
-
Format
- Liquid
-
Concentration
- Lot specific
-
Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
-
Agent conservateur
- Sodium azide
-
Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
Conseil sur la manipulation
- Avoid repeated freeze-thaw cycles.
-
Stock
- -20 °C
-
Stockage commentaire
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
-
-
- CHRNB2 (Cholinergic Receptor, Nicotinic, beta 2 (Neuronal) (CHRNB2))
-
Autre désignation
- CHRNB2
-
Sujet
-
Mutations in nAChRs are found in a rare form of nocturnal frontal lobe epilepsy . Previously, some nAChR mutations have been described that are associated with additional neurological features such as psychiatric disorders or cognitive defects. A new CHRNB2 mutation located in transmembrane region 3 (M3), outside the known ADNFLE mutation cluster. The CHRNB2 mutation I312M, which occurred de novo in twins, markedly increases the receptor's sensitivity to acetylcholine. Phenotypically, the mutation is associated not only with typical ADNFLE, but also with distinct deficits in memory. The cognitive problems are most obvious in tasks requiring the organization and storage of verbal information.
Alias Symbols: EFNL3, nAChRB2
Protein Interaction Partner: CRELD2, CHRNA4, CHRNA2,
Protein Size: 502 -
Poids moléculaire
- 57 kDa
-
ID gène
- 1141
-
NCBI Accession
- NM_000748, NP_000739
-
UniProt
- P17787
-
Pathways
- Sensory Perception of Sound, Feeding Behaviour
Antigène
-
