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CYP2E1 anticorps (C-Term)

Cet anticorps Lapin Polyclonal détecte spécifiquement CYP2E1 dans WB. Il présente une réactivité avec des échantillons de Humain, Souris, Rat, Lapin, Chien, Cheval, Cobaye, Boeuf (Vache) et Mouton.
N° du produit ABIN310147
150,78 €
Plus frais de livraison 40,00 € et TVA
Destination: France
Envoi sous 6 à 9 jours ouvrables

Aperçu rapide pour CYP2E1 anticorps (C-Term) (ABIN310147)

Antigène

Voir toutes CYP2E1 Anticorps
CYP2E1 (Cytochrome P450, Family 2, Subfamily E, Polypeptide 1 (CYP2E1))

Reactivité

  • 80
  • 55
  • 45
  • 17
  • 5
  • 4
  • 3
  • 3
  • 2
  • 2
  • 2
Humain, Souris, Rat, Lapin, Chien, Cheval, Cobaye, Boeuf (Vache), Mouton

Hôte

  • 87
  • 9
  • 2
Lapin

Clonalité

  • 82
  • 16
Polyclonal

Conjugué

  • 54
  • 11
  • 4
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Cet anticorp CYP2E1 est non-conjugé

Application

  • 76
  • 34
  • 19
  • 16
  • 15
  • 11
  • 11
  • 10
  • 10
  • 4
  • 4
  • 3
  • 1
  • 1
Western Blotting (WB)
  • Épitope

    • 17
    • 12
    • 6
    • 4
    • 4
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    C-Term

    Séquence

    QEFPDPEKFK PEHFLNENGK FKYSDYFKPF STGKRVCAGE GLARMELFLL

    Homologie

    Cow: 79%, Dog: 86%, Guinea Pig: 92%, Horse: 79%, Human: 100%, Mouse: 92%, Rabbit: 93%, Rat: 92%, Sheep: 79%

    Attributs du produit

    This is a rabbit polyclonal antibody against CYP2E1. It was validated on Western Blot using a cell lysate as a positive control.

    Purification

    Affinity Purified

    Immunogène

    The immunogen is a synthetic peptide directed towards the C terminal region of human CYP2E1
  • Indications d'application

    Optimal working dilutions should be determined experimentally by the investigator.

    Commentaires

    Antigen size: 493 AA

    Restrictions

    For Research Use only
  • Format

    Liquid

    Concentration

    Lot specific

    Buffer

    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

    Agent conservateur

    Sodium azide

    Précaution d'utilisation

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Conseil sur la manipulation

    Avoid repeated freeze-thaw cycles.

    Stock

    -20 °C

    Stockage commentaire

    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Antigène

    CYP2E1 (Cytochrome P450, Family 2, Subfamily E, Polypeptide 1 (CYP2E1))

    Autre désignation

    CYP2E1

    Sujet

    CYP2E1 is a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the endoplasmic reticulum and is induced by ethanol, the diabetic state, and starvation. The enzyme metabolizes both endogenous substrates, such as ethanol, acetone, and acetal, as well as exogenous substrates including benzene, carbon tetrachloride, ethylene glycol, and nitrosamines which are premutagens found in cigarette smoke. Due to its many substrates, this enzyme may be involved in such varied processes as gluconeogenesis, hepatic cirrhosis, diabetes, and cancer.This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the endoplasmic reticulum and is induced by ethanol, the diabetic state, and starvation. The enzyme metabolizes both endogenous substrates, such as ethanol, acetone, and acetal, as well as exogenous substrates including benzene, carbon tetrachloride, ethylene glycol, and nitrosamines which are premutagens found in cigarette smoke. Due to its many substrates, this enzyme may be involved in such varied processes as gluconeogenesis, hepatic cirrhosis, diabetes, and cancer.
    Alias Symbols: CPE1, CYP2E, P450-J, P450C2E
    Protein Interaction Partner: UBC, ABCA5, LAMC3, NMI, PTN, POR, MAFG, GATM, ECHS1, CYB5A, AGXT2, RPL13A, CLU, STUB1, AMFR, FANCG,
    Protein Size: 493

    Poids moléculaire

    54 kDa

    ID gène

    1571

    NCBI Accession

    NM_000773, NP_000764

    UniProt

    P05181
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