PSMB1 anticorps (Middle Region)
(1 reference)Aperçu rapide pour PSMB1 anticorps (Middle Region) (ABIN503974)
Antigène
Voir toutes PSMB1 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- Middle Region
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Séquence
- NNKAMTTGAI AAMLSTILYS RRFFPYYVYN IIGGLDEEGK GAVYSFDPVG
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Homologie
- Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Yeast: 93%, Zebrafish: 93%
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Attributs du produit
- This is a rabbit polyclonal antibody against PSMB1. It was validated on Western Blot using a cell lysate as a positive control.
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Purification
- Affinity Purified
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Immunogène
- The immunogen is a synthetic peptide directed towards the middle region of human PSMB1
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anti-Proteasome (Prosome, Macropain) Subunit, beta Type, 1 (PSMB1) (AA 29-241) antibody
PSMB1 Reactivité: Humain WB, IF Hôte: Lapin Polyclonal unconjugated
anti-Proteasome (Prosome, Macropain) Subunit, beta Type, 1 (PSMB1) (AA 214-241), (C-Term) antibodyPSMB1 Reactivité: Humain, Souris WB, IF, FACS, IHC (p) Hôte: Lapin Polyclonal RB22483 unconjugated
anti-Proteasome (Prosome, Macropain) Subunit, beta Type, 1 (PSMB1) antibodyPSMB1 Reactivité: Humain, Souris, Rat WB, IF Hôte: Lapin Polyclonal unconjugated
anti-Proteasome (Prosome, Macropain) Subunit, beta Type, 1 (PSMB1) (AA 29-241) antibodyPSMB1 Reactivité: Humain WB, ELISA Hôte: Lapin Polyclonal unconjugated
anti-Proteasome (Prosome, Macropain) Subunit, beta Type, 1 (PSMB1) (AA 107-156) antibodyPSMB1 Reactivité: Humain, Souris, Rat, Lapin, Boeuf (Vache), Chien, Cobaye, Cheval, Roussette (Chauve-souris), Poulet, Singe, Porc, Xenopus laevis WB Hôte: Lapin Polyclonal unconjugated
anti-Proteasome (Prosome, Macropain) Subunit, beta Type, 1 (PSMB1) (Middle Region) antibodyPSMB1 Reactivité: Humain, Souris, Rat, Poisson zèbre (Danio rerio), Lapin, Saccharomyces cerevisiae, Boeuf (Vache), Chien, Cobaye, Cheval WB Hôte: Lapin Polyclonal unconjugated
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Indications d'application
- Optimal working dilutions should be determined experimentally by the investigator.
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Commentaires
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Antigen size: 241 AA
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- Lot specific
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Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Conseil sur la manipulation
- Avoid repeated freeze-thaw cycles.
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Stock
- -20 °C
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Stockage commentaire
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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: "Large-scale mapping of human protein-protein interactions by mass spectrometry. ..." dans: Molecular systems biology, Vol. 3, pp. 89, (2007) (PubMed).
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- PSMB1 (Proteasome (Prosome, Macropain) Subunit, beta Type, 1 (PSMB1))
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Autre désignation
- PSMB1
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Sujet
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The proteasome is a multicatalytic proteinase complex with a highly ordered ring-shaped 20S core structure. The core structure is composed of 4 rings of 28 non-identical subunits, 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. PSMB1 is a member of the proteasome B-type family, also known as the T1B family, that is a 20S core beta subunit. This gene is tightly linked to the TBP (TATA-binding protein) gene in human and in mouse, and is transcribed in the opposite orientation in both species.The proteasome is a multicatalytic proteinase complex with a highly ordered ring-shaped 20S core structure. The core structure is composed of 4 rings of 28 non-identical subunits, 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. This gene encodes a member of the proteasome B-type family, also known as the T1B family, that is a 20S core beta subunit. This gene is tightly linked to the TBP (TATA-binding protein) gene in human and in mouse, and is transcribed in the opposite orientation in both species. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Alias Symbols: FLJ25321, HC5, KIAA1838, PMSB1, PSC5
Protein Interaction Partner: MAPRE3, UBC, TRAF1, TRIM27, KRT15, KRT13, KIFC3, CDKN1B, PSMA7, HAUS2, PSMD14, PSEN1, PSMG3, PSMB8, PSMB7, PSMB6, PSMB5, PSMB4, PSMB3, PSMB2, PSMA6, PSMA5, PSMA4, PSMA3, PSMA1, HNRNPA2B1, DDB2, SMEK1, AP3M1, PSME4, RPP38, RPP30, SEC13, PYCRL, HECW2, PSMA2
Protein Size: 241 -
Poids moléculaire
- 26 kDa
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ID gène
- 5689
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NCBI Accession
- NM_002793, NP_002784
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UniProt
- P20618
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Pathways
- Mitotic G1-G1/S Phases, DNA Replication, Synthesis of DNA
Antigène
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