SCNN1B anticorps (C-Term)
Aperçu rapide pour SCNN1B anticorps (C-Term) (ABIN183112)
Antigène
Voir toutes SCNN1B AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- C-Term
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Séquence
- QPDTAPRSPN TGPYPSEQAL PIPGTPPPNY DSLRLQPLDV IESDSEGDAI
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Homologie
- Cow: 100%, Dog: 100%, Goat: 100%, Guinea Pig: 93%, Horse: 92%, Human: 100%, Mouse: 86%, Pig: 100%, Rabbit: 93%, Rat: 86%
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Attributs du produit
- This is a rabbit polyclonal antibody against SCNN1B. It was validated on Western Blot using a cell lysate as a positive control.
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Purification
- Affinity Purified
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Immunogène
- The immunogen is a synthetic peptide directed towards the C terminal region of human SCNN1B
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Indications d'application
- Optimal working dilutions should be determined experimentally by the investigator.
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Commentaires
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Antigen size: 640 AA
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- Lot specific
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Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Conseil sur la manipulation
- Avoid repeated freeze-thaw cycles.
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Stock
- -20 °C
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Stockage commentaire
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- SCNN1B (Sodium Channel, Nonvoltage-Gated 1, beta (SCNN1B))
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Autre désignation
- SCNN1B
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Sujet
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When expressed in the bladder epithelium, the protein encoded by the SCNN1B gene might be implicated in the mechanosensory transduction in the bladder afferent pathways, thereby inducing detrusor instability by outlet obstruction. Common variants of this gene confer susceptibility to human essential hypertension.
Alias Symbols: BESC1, ENaCb, SCNEB, ENaCbeta
Protein Interaction Partner: NEDD4L, SERP1, SCNN1G, SCNN1A, COMMD1, UBC, USP2, RAF1, NEDD4, TSC22D3, SGK1, EPN1, AP1M2, NFASC, CNTN1, WWP2, SCNN1D, ANK3, STX1A, ITCH, HECW1,
Protein Size: 640 -
Poids moléculaire
- 70 kDa
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ID gène
- 6338
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NCBI Accession
- NM_000336, NP_000327
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UniProt
- P51168
Antigène
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