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VDAC1 anticorps (C-Term)

Il existe 3+ publications pour ce produit. L’anticorps anti-VDAC1 Polyclonal Lapin est utilisé pour la détection de VDAC1 dans des échantillons de Humain, Rat, Souris, Lapin, Boeuf (Vache), Chien, Mouton, Cheval, Cobaye et Poisson zèbre (Danio rerio). Il a été validé pour WB et IHC.
N° du produit ABIN183134
150,78 €
Plus frais de livraison 40,00 € et TVA
Destination: France
Envoi sous 6 à 9 jours ouvrables

Aperçu rapide pour VDAC1 anticorps (C-Term) (ABIN183134)

Antigène

Voir toutes VDAC1 Anticorps
VDAC1 (Voltage-Dependent Anion Channel 1 (VDAC1))

Reactivité

  • 99
  • 51
  • 39
  • 5
  • 5
  • 4
  • 4
  • 3
  • 3
  • 3
  • 3
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Humain, Rat, Souris, Lapin, Boeuf (Vache), Chien, Mouton, Cheval, Cobaye, Poisson zèbre (Danio rerio)

Hôte

  • 78
  • 28
  • 2
Lapin

Clonalité

  • 59
  • 49
Polyclonal

Conjugué

  • 54
  • 7
  • 5
  • 5
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Cet anticorp VDAC1 est non-conjugé

Application

  • 89
  • 61
  • 38
  • 24
  • 21
  • 13
  • 13
  • 9
  • 7
  • 5
  • 4
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
Western Blotting (WB), Immunohistochemistry (IHC)
  • Épitope

    • 18
    • 15
    • 6
    • 6
    • 5
    • 4
    • 4
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    C-Term

    Séquence

    SAKVNNSSLI GLGYTQTLKP GIKLTLSALL DGKNVNAGGH KLGLGLEFQA

    Homologie

    Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Sheep: 100%, Zebrafish: 86%

    Attributs du produit

    This is a rabbit polyclonal antibody against VDAC1. It was validated on Western Blot and immunohistochemistry.

    Purification

    Protein A purified

    Immunogène

    The immunogen is a synthetic peptide directed towards the C terminal region of human VDAC1
  • Indications d'application

    Optimal working dilutions should be determined experimentally by the investigator.

    Commentaires

    Antigen size: 283 AA

    Restrictions

    For Research Use only
  • Format

    Liquid

    Concentration

    Lot specific

    Buffer

    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

    Agent conservateur

    Sodium azide

    Précaution d'utilisation

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Conseil sur la manipulation

    Avoid repeated freeze-thaw cycles.

    Stock

    -20 °C

    Stockage commentaire

    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Rousset, Nguyen, Grange, Morel, Lardy: "Heme oxygenase-1 regulates matrix metalloproteinase MMP-1 secretion and chondrocyte cell death via Nox4 NADPH oxidase activity in chondrocytes." dans: PLoS ONE, Vol. 8, Issue 6, pp. e66478, (2013) (PubMed).

    Arduíno, Esteves, Cortes, Silva, Patel, Grazina, Swerdlow, Oliveira, Cardoso: "Mitochondrial metabolism in Parkinson's disease impairs quality control autophagy by hampering microtubule-dependent traffic." dans: Human molecular genetics, Vol. 21, Issue 21, pp. 4680-702, (2012) (PubMed).

    Chen, Martin, Maya-Mendoza, Tang, Lovri?, Sims, Jackson: "Reduced expression of lamin A/C results in modified cell signaling and metabolism coupled with changes in expression of structural proteins." dans: Journal of proteome research, Vol. 8, Issue 11, pp. 5196-211, (2009) (PubMed).

  • Antigène

    VDAC1 (Voltage-Dependent Anion Channel 1 (VDAC1))

    Autre désignation

    VDAC1

    Sujet

    The voltage-dependent anion-selective channel 1 (VDAC1) functions as a channel in membranous structures for the outer mitochondrial membrane, the cell membrane, endosomes, caveolae, the sarcoplasmatic reticulum, synaptosomes, and post-synaptic density fraction. A major function of VDAC1 in the plasma membrane is that of a NADH(-ferricyanide) reductase that may be involved in the maintenance of cellular redox homeostasis.
    Alias Symbols: PORIN, VDAC-1
    Protein Interaction Partner: UBC, KLHL40, SPRTN, MDM2, ADRB2, ASB14, ASB17, PARK2, BAG3, env, VCAM1, HK1, ATF2, FMNL1, TUBA1B, MDC1, CAV1, Htt, SFXN3, SUGP1, UBAP2, UFM1, ACAD9, MGAT4B, ACAA2, ZMPSTE24, VAPA, ALDH5A1, SF1, VDAC3, VDAC2, UBA52, TIAL1, FLOT2, CDK2, SIRT7, SUMO4, MAPK3,
    Protein Size: 283

    Poids moléculaire

    31 kDa

    ID gène

    7416

    NCBI Accession

    NM_003374, NP_003365

    UniProt

    Q5FVE7
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