ABCB6 anticorps (AA 430-465)
(2 références)
Aperçu rapide pour ABCB6 anticorps (AA 430-465) (ABIN129698)
Antigène
Voir toutes ABCB6 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
-
-
Épitope
- AA 430-465
-
N° du produit (Fournisseur)
- 600-401-945
-
Fournisseur
- Rockland
-
Fonction
- ABCB6 Antibody
-
Réactivité croisée (Details)
- This affinity-purified antibody is directed against human ABCB6 protein.
-
Attributs du produit
- Synonyms: rabbit anti-ABCB6 Antibody, ABCB 6, ABCB-6, ABC transporter umat antibody, ABC14 antibody, ATP binding cassette sub family B member 6, mitochondrial precursor antibody, mitochondrial precursor ABC transporter 3, Mt-ABC transporter 3
-
Purification
- The product was affinity purified from monospecific antiserum by immunoaffinity purification.
-
Stérilité
- Sterile filtered
-
Immunogène
-
Immunogen: This affinity purified antibody was prepared from whole rabbit serum produced by repeated immunizations with a synthetic peptide corresponding to an internal region near amino acids 430-465 of human ABCB6 protein.
Immunogen Type: Conjugated Peptide
-
Isotype
- IgG
-
-
anti-ATP-Binding Cassette, Sub-Family B (MDR/TAP), Member 6 (ABCB6) (AA 743-842) antibody
ABCB6 Reactivité: Humain WB, ELISA Hôte: Souris Polyclonal unconjugated
anti-ATP-Binding Cassette, Sub-Family B (MDR/TAP), Member 6 (ABCB6) (AA 590-842) antibodyABCB6 Reactivité: Humain WB, IHC, ICC, IP Hôte: Lapin Polyclonal unconjugated
anti-ATP-Binding Cassette, Sub-Family B (MDR/TAP), Member 6 (ABCB6) antibodyABCB6 Reactivité: Humain, Souris, Rat WB, ELISA Hôte: Lapin Polyclonal unconjugated
anti-ATP-Binding Cassette, Sub-Family B (MDR/TAP), Member 6 (ABCB6) (AA 743-842) antibodyABCB6 Reactivité: Humain WB, ELISA Hôte: Souris Monoclonal 3E1 unconjugated
anti-ATP-Binding Cassette, Sub-Family B (MDR/TAP), Member 6 (ABCB6) (AA 401-520) antibodyABCB6 Reactivité: Humain, Souris, Rat ELISA, IF (cc), IF (p), IHC (p), IHC (fro) Hôte: Lapin Polyclonal unconjugated
anti-ATP-Binding Cassette, Sub-Family B (MDR/TAP), Member 6 (ABCB6) (AA 431-480) antibodyABCB6 Reactivité: Humain, Souris, Rat, Chien, Cobaye, Cheval, Lapin, Roussette (Chauve-souris), Singe, Porc WB Hôte: Lapin Polyclonal unconjugated
anti-ATP-Binding Cassette, Sub-Family B (MDR/TAP), Member 6 (ABCB6) (AA 818-842), (C-Term) antibodyABCB6 Reactivité: Humain WB, IHC, ICC Hôte: Lapin Polyclonal unconjugated
-
-
Indications d'application
-
Application Note: This affinity-purified antibody has been tested for use in ELISA and western blot. Specific conditions for reactivity should be optimized by the end user. Expect a band approximately 94 kDa in size corresponding to ABCB6 protein by western blotting in the appropriate cell lysate or extract.
Western Blot Dilution: 1:1,000 - 1:5,000
ELISA Dilution: 1:40,000 - 1:130,000
Other: User Optimized
-
Restrictions
- For Research Use only
-
-
-
Format
- Liquid
-
Concentration
- 1.0 mg/ml
-
Buffer
-
Buffer: 0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2
Stabilizer: None
Preservative: 0.01 % (w/v) Sodium Azide -
Agent conservateur
- Sodium azide
-
Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
Stock
- 4 °C,-20 °C
-
Stockage commentaire
- Store vial at -20° C prior to opening. Aliquot contents and freeze at -20° C or below for extended storage. Avoid cycles of freezing and thawing. Centrifuge product if not completely clear after standing at room temperature. This product is stable for several weeks at 4° C as an undiluted liquid. Dilute only prior to immediate use.
-
Date de péremption
- 12 months
-
-
-
: "Dormant cancer cells accumulate high protoporphyrin IX levels and are sensitive to 5-aminolevulinic acid-based photodynamic therapy." dans: Scientific reports, Vol. 6, pp. 36478, (2016) (PubMed).
: "Conserved intramolecular disulfide bond is critical to trafficking and fate of ATP-binding cassette (ABC) transporters ABCB6 and sulfonylurea receptor 1 (SUR1)/ABCC8." dans: The Journal of biological chemistry, Vol. 286, Issue 10, pp. 8481-92, (2011) (PubMed).
-
-
- ABCB6 (ATP-Binding Cassette, Sub-Family B (MDR/TAP), Member 6 (ABCB6))
-
Autre désignation
- ABCB6
-
Sujet
- Background: This antibody is designed, produced, and validated as part of a collaboration with the National Cancer Institute (NCI) and is suitable for Cancer, Immunology and Nuclear Signaling research. ABCB6 (ATP-binding cassette sub-family B member 6) is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABCB6 is a membrane-associated protein that transports various molecules across the extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, DR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the MDR/TAP subfamily. Members of the MDR/TAP subfamily confer multi-drug resistance (MDR) to cancer cells and are also involved in antigen presentation. ABCB6 also likely plays a role in mitochondrial function. Localized to 2q26, this gene is considered a candidate gene for lethal neonatal metabolic syndrome, a disorder of mitochondrial function. Anti-ABCB6 is ideal for researchers interested in heme synthesis.
-
ID gène
- 10058, 13123949
-
UniProt
- Q9NP58
-
Pathways
- Transition Metal Ion Homeostasis
Antigène
-
