ABCG2 anticorps (Center)
Cet anticorps Lapin Polyclonal détecte spécifiquement ABCG2 dans WB, FACS, IF et IHC (p). Il présente une réactivité avec des échantillons de Humain.
N° du produit ABIN388306
434,77 €
Plus frais de livraison 40,00 € et TVA
400 μL
Destination:
France
Envoi sous 14 à 17 jours ouvrables
Aperçu rapide pour ABCG2 anticorps (Center) (ABIN388306)
Antigène
Voir toutes ABCG2 Anticorps
ABCG2
(ATP-Binding Cassette, Sub-Family G (WHITE), Member 2 (ABCG2))
Reactivité
Humain
Hôte
Lapin
Clonalité
Polyclonal
Conjugué
Cet anticorp ABCG2 est non-conjugé
Application
Western Blotting (WB), Flow Cytometry (FACS), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
Clone
RB13782
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Épitope
- AA 305-335, Center
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Specificité
- This ABCG2 (BCRP) antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 313~342 amino acids from the center region of human ABCG2.
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Purification
- This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
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Immunogène
- This ABCG2 (BCRP) antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 305-335 AA from the Central region of human ABCG2 (BCRP).
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Isotype
- Ig Fraction
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anti-ATP-Binding Cassette, Sub-Family G (WHITE), Member 2 (ABCG2) (AA 137-168), (N-Term) antibody
ABCG2 Reactivité: Humain, Souris, Rat WB, IHC Hôte: Lapin Polyclonal unconjugated
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Indications d'application
- WB = 1:1000, IF = 1:10-50, FACS = 1:10-50, IHC (p) = 1:50-100
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 2 mg/mL
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Buffer
- PBS with 0.09 % (W/V) sodium azide
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- 4 °C/-20 °C
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Stockage commentaire
- Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
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Date de péremption
- 6 months
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- ABCG2 (ATP-Binding Cassette, Sub-Family G (WHITE), Member 2 (ABCG2))
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Autre désignation
- ABCG2 (BCRP)
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Sujet
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ABCG2 is a membrane-associated protein included in the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the White subfamily. Alternatively referred to as a breast cancer resistance protein, this protein functions as a xenobiotic transporter which may play a major role in multi-drug resistance. It likely serves as a cellular defense mechanism in response to mitoxantrone and anthracycline exposure. Significant expression of this protein has been observed in the placenta, which may suggest a potential role for this molecule in placenta tissue.
Synonyms: ATP-binding cassette sub-family G member 2, Placenta-specific ATP-binding cassette transporter, Breast cancer resistance protein, Mitoxantrone resistance-associated protein, CD338 antigen, CDw338, ABCP, BCRP, BCRP1, MXR -
Poids moléculaire
- 72314 DA
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ID gène
- 9429
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UniProt
- Q9UNQ0
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Pathways
- Transition Metal Ion Homeostasis
Antigène
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