AKAP1 anticorps
Aperçu rapide pour AKAP1 anticorps (ABIN498433)
Antigène
Voir toutes AKAP1 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
-
-
Specificité
- This antibody detects endogenous levels of AKAP149 protein. (region surrounding asn306)
-
Réactivité croisée (Details)
- Species reactivity (tested):Human.
-
Purification
- Affinity-Chromatography using epitope-specific immunogen
-
-
anti-A Kinase (PRKA) Anchor Protein 1 (AKAP1) (Internal Region) antibody
AKAP1 Reactivité: Humain, Souris WB, IHC, IF, ELISA, ICC Hôte: Lapin Polyclonal unconjugated
anti-A Kinase (PRKA) Anchor Protein 1 (AKAP1) (AA 375-425) antibodyAKAP1 Reactivité: Humain IHC, IF (p) Hôte: Lapin Polyclonal unconjugated
anti-A Kinase (PRKA) Anchor Protein 1 (AKAP1) (AA 66-212) antibodyAKAP1 Reactivité: Humain, Rat WB, IHC, IF, IP Hôte: Souris Monoclonal 6-AKAP149 unconjugated
anti-A Kinase (PRKA) Anchor Protein 1 (AKAP1) (AA 806-903) antibodyAKAP1 Reactivité: Humain WB, ELISA Hôte: Souris Polyclonal unconjugated
anti-A Kinase (PRKA) Anchor Protein 1 (AKAP1) (AA 281-330) antibodyAKAP1 Reactivité: Humain WB, IHC, IF, ELISA Hôte: Lapin Polyclonal unconjugated
anti-A Kinase (PRKA) Anchor Protein 1 (AKAP1) (Center) antibodyAKAP1 Reactivité: Humain, Souris, Rat WB, IHC, IF Hôte: Lapin Polyclonal unconjugated
anti-A Kinase (PRKA) Anchor Protein 1 (AKAP1) (AA 1-903) antibodyAKAP1 Reactivité: Humain WB Hôte: Souris Polyclonal unconjugated
anti-A Kinase (PRKA) Anchor Protein 1 (AKAP1) (AA 541-571) antibodyAKAP1 Reactivité: Humain WB Hôte: Lapin Polyclonal unconjugated
anti-A Kinase (PRKA) Anchor Protein 1 (AKAP1) (AA 375-425) antibodyAKAP1 Reactivité: Humain WB, IP, IHC (fp) Hôte: Lapin Polyclonal unconjugated
anti-A Kinase (PRKA) Anchor Protein 1 (AKAP1) (C-Term) antibodyAKAP1 Reactivité: Humain WB Hôte: Lapin Polyclonal unconjugated
-
-
Indications d'application
-
Western Blot: 1/500 - 1/1000. Immunohistochemistry: 1/50 - 1/200. Immunofluorescence: 1/50 - 1/200.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
Restrictions
- For Research Use only
-
-
-
Concentration
- 1.0 mg/mL
-
Buffer
- Phosphate buffered saline (PBS), pH ~7.2, 0.05 % Sodium Azide
-
Agent conservateur
- Sodium azide
-
Précaution d'utilisation
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
Conseil sur la manipulation
- Avoid repeated freezing and thawing.
-
Stock
- 4 °C/-20 °C
-
Stockage commentaire
- Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
-
-
- AKAP1 (A Kinase (PRKA) Anchor Protein 1 (AKAP1))
-
Autre désignation
- AKAP1
-
Sujet
- The type II cAMP-protein kinase (PKA) is a multifunctional kinase with a broad range of substrates. Specificity of PKA signaling is thought to be mediated by the compartmentalization of the kinase to specific sites within the cell. To maintain this specific localization, the R subunit (RII) of PKA interacts with specific RII-anchoring proteins. This family of proteins has been designated A-kinase anchoring proteins (AKAP). Members of this family, including MAP2 (microtubule-associated protein 2), neuronally expressed AKAP 79 and AKAP 150, and the DNA binding AKAP 95, display differential tissue specificity and localization. Evidence suggests that AKAP 79 and AKAP 150 are both capable of anchoring PKA to postsynaptic densities (PSD), which are a network of proteins located on the internal surfaces of excitatory synapses.Synonyms: A kinase anchor protein 1 mitochondrial, A-kinase anchor protein 149 kDa, AKAP-1, AKAP149, Dual specificity A-kinase-anchoring protein 1, PRKA1, Protein kinase A-anchoring protein 1, Spermatid A-kinase anchor protein 84
-
Poids moléculaire
- approx. 90 kDa
-
ID gène
- 8165
-
NCBI Accession
- NP_003479
-
UniProt
- Q92667
-
Pathways
- Synaptic Membrane
Antigène
-
