AKR1C3 anticorps (N-Term)
(1 reference)Aperçu rapide pour AKR1C3 anticorps (N-Term) (ABIN654117)
Antigène
Voir toutes AKR1C3 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
Clone
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Épitope
- AA 10-36, N-Term
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Purification
- This antibody is purified through a protein A column, followed by peptide affinity purification.
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Immunogène
- This AKR1C3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 10-36 amino acids from the N-terminal region of human AKR1C3.
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Isotype
- Ig Fraction
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anti-Aldo-Keto Reductase Family 1, Member C3 (3-alpha Hydroxysteroid Dehydrogenase, Type II) (AKR1C3) (C-Term) antibody
KO Validated AKR1C3 Reactivité: Humain WB, IF, IP, ICC, IHC (p) Hôte: Lapin Polyclonal unconjugated
anti-Aldo-Keto Reductase Family 1, Member C3 (3-alpha Hydroxysteroid Dehydrogenase, Type II) (AKR1C3) (AA 1-323) antibodyAKR1C3 Reactivité: Humain WB, IF, IP Hôte: Lapin Polyclonal unconjugated
anti-Aldo-Keto Reductase Family 1, Member C3 (3-alpha Hydroxysteroid Dehydrogenase, Type II) (AKR1C3) antibodyAKR1C3 Reactivité: Humain, Souris, Rat WB, ELISA, IHC, IF, ICC Hôte: Lapin Polyclonal unconjugated
anti-Aldo-Keto Reductase Family 1, Member C3 (3-alpha Hydroxysteroid Dehydrogenase, Type II) (AKR1C3) (AA 1-323) antibodyAKR1C3 Reactivité: Humain WB, ELISA, IHC, IP Hôte: Lapin Polyclonal unconjugated
anti-Aldo-Keto Reductase Family 1, Member C3 (3-alpha Hydroxysteroid Dehydrogenase, Type II) (AKR1C3) (AA 1-323) antibodyAKR1C3 Reactivité: Humain WB Hôte: Souris Polyclonal unconjugated
anti-Aldo-Keto Reductase Family 1, Member C3 (3-alpha Hydroxysteroid Dehydrogenase, Type II) (AKR1C3) (AA 107-135) antibodyAKR1C3 Reactivité: Humain WB, IHC (p) Hôte: Lapin Polyclonal RB31739 unconjugated
anti-Aldo-Keto Reductase Family 1, Member C3 (3-alpha Hydroxysteroid Dehydrogenase, Type II) (AKR1C3) antibodyAKR1C3 Reactivité: Humain, Souris WB, IF Hôte: Lapin Polyclonal unconjugated
anti-Aldo-Keto Reductase Family 1, Member C3 (3-alpha Hydroxysteroid Dehydrogenase, Type II) (AKR1C3) (C-Term) antibodyVerified AKR1C3 Reactivité: Humain WB, ELISA, IHC Hôte: Chèvre Polyclonal unconjugated
anti-Aldo-Keto Reductase Family 1, Member C3 (3-alpha Hydroxysteroid Dehydrogenase, Type II) (AKR1C3) antibodyAKR1C3 Reactivité: Humain ELISA, IF, FACS Hôte: Lapin Monoclonal 4D12 unconjugated Recombinant Antibody
anti-Aldo-Keto Reductase Family 1, Member C3 (3-alpha Hydroxysteroid Dehydrogenase, Type II) (AKR1C3) antibodyAKR1C3 Reactivité: Humain WB, IF Hôte: Lapin Monoclonal unconjugated
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Indications d'application
- WB: 1:1000. FC: 1:10~50
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Restrictions
- For Research Use only
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Format
- Liquid
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Buffer
- Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- 4 °C,-20 °C
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Stockage commentaire
- Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
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Date de péremption
- 6 months
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: "Induction of PGF2? synthesis by cortisol through GR dependent induction of CBR1 in human amnion fibroblasts." dans: Endocrinology, Vol. 155, Issue 8, pp. 3017-24, (2014) (PubMed).
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- AKR1C3 (Aldo-Keto Reductase Family 1, Member C3 (3-alpha Hydroxysteroid Dehydrogenase, Type II) (AKR1C3))
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Autre désignation
- AKR1C3
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Sujet
- This gene encodes a member of the aldo/keto reductase superfamily, which consists of more than 40 known enzymes and proteins. These enzymes catalyze the conversion of aldehydes and ketones to their corresponding alcohols by utilizing NADH and/or NADPH as cofactors. The enzymes display overlapping but distinct substrate specificity. This enzyme catalyzes the reduction of prostaglandin (PG) D2, PGH2 and phenanthrenequinone (PQ), and the oxidation of 9alpha,11beta-PGF2 to PGD2. It may play an important role in the pathogenesis of allergic diseases such as asthma, and may also have a role in controlling cell growth and/or differentiation. This gene shares high sequence identity with three other gene members and is clustered with those three genes at chromosome 10p15-p14.
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Poids moléculaire
- 36853
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ID gène
- 8644
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NCBI Accession
- NP_001240837, NP_003730
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UniProt
- P42330
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Pathways
- Retinoic Acid Receptor Signaling Pathway, Steroid Hormone Biosynthesis, Regulation of Hormone Metabolic Process, Regulation of Hormone Biosynthetic Process, C21-Steroid Hormone Metabolic Process, Protein targeting to Nucleus
Antigène
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