CPSF1 anticorps (Middle Region)
Aperçu rapide pour CPSF1 anticorps (Middle Region) (ABIN310073)
Antigène
Voir toutes CPSF1 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- Middle Region
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Séquence
- GCYDMWTVIA PVRKEEEDNP KGEGTEQEPS TTPEADDDGR RHGFLILSRE
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Homologie
- Horse: 79%, Human: 100%, Rat: 77%
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Attributs du produit
- This is a rabbit polyclonal antibody against CPSF1. It was validated on Western Blot using a cell lysate as a positive control.
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Purification
- Affinity Purified
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Immunogène
- The immunogen is a synthetic peptide directed towards the middle region of human CPSF1
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Indications d'application
- Optimal working dilutions should be determined experimentally by the investigator.
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Commentaires
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Antigen size: 1443 AA
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- Lot specific
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Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Conseil sur la manipulation
- Avoid repeated freeze-thaw cycles.
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Stock
- -20 °C
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Stockage commentaire
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- CPSF1 (Cleavage and Polyadenylation Specific Factor 1, 160kDa (CPSF1))
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Autre désignation
- CPSF1
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Sujet
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CPSF1 is a component of the cleavage and polyadenylation specificity factor (CPSF) complex that plays a key role in pre-mRNA 3'-end formation, recognizing the AAUAAA signal sequence and interacting with poly(A) polymerase and other factors to bring about cleavage and poly(A) addition. This subunit is involved in the RNA recognition step of the polyadenylation reaction.
Alias Symbols: CPSF160, HSU37012, P/cl.18
Protein Interaction Partner: REL, RBBP6, UBC, STAU1, LGR4, WWOX, RPA3, RPA2, RPA1, EED, EZH2, NEDD4, TARDBP, ICK, CLK2, HDAC6, NPM1, IL7R, HMOX1, TUT1, FIP1L1, RNPC3, WDR33, CPSF2, MED8, CPSF3, GTF3C3, POLR2A, COPS6, CUL3, SIRT7, SMARCAD1, CSTF2T, PAPOLA, CSTF3, GLIS2, RRAGA, TBP, TA
Protein Size: 1443 -
Poids moléculaire
- 161 kDa
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ID gène
- 29894
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NCBI Accession
- NM_013291, NP_037423
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UniProt
- Q10570
Antigène
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