Il existe 1 publication pour ce produit.
L’anticorps anti-GGA1 Polyclonal Lapin est utilisé pour la détection de GGA1 dans des échantillons de Humain et Souris. Il a été validé pour WB et IF.
This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
Immunogène
This GGA1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1-30 amino acids from the N-terminal region of human GGA1.
GGA1
Reactivité: Humain
IF (cc), IF (p)
Hôte: Lapin
Polyclonal
AbBy Fluor® 488
Indications d'application
IF: 1:10~50. WB: 1:1000
Restrictions
For Research Use only
Format
Liquid
Buffer
Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
Agent conservateur
Sodium azide
Précaution d'utilisation
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Stock
4 °C,-20 °C
Stockage commentaire
Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
Date de péremption
6 months
von Arnim, Spoelgen, Peltan, Deng, Courchesne, Koker, Matsui, Kowa, Lichtenthaler, Irizarry, Hyman: "GGA1 acts as a spatial switch altering amyloid precursor protein trafficking and processing." dans: The Journal of neuroscience : the official journal of the Society for Neuroscience, Vol. 26, Issue 39, pp. 9913-22, (2006) (PubMed).
GGA1 is a member of the Golgi-localized, gamma adaptin ear-containing, ARF-binding (GGA) protein family. Members of this family are ubiquitous coat proteins that regulate the trafficking of proteins between the trans-Golgi network and the lysosome. These proteins share an amino-terminal VHS domain which mediates sorting of the mannose 6-phosphate receptors at the trans-Golgi network. They also contain a carboxy-terminal region with homology to the ear domain of gamma-adaptins.